PMID- 23743889
OWN - NLM
STAT- MEDLINE
DCOM- 20140116
LR  - 20211021
IS  - 1573-2606 (Electronic)
IS  - 1389-9155 (Linking)
VI  - 14
IP  - 2
DP  - 2013 Jun
TI  - HIV and thyroid dysfunction.
PG  - 127-31
LID - 10.1007/s11154-013-9248-6 [doi]
AB  - Human Immunodeficiency virus (HIV) infection and Acquired Immunodeficiency 
      Syndrome (AIDS) are associated with dysfunction of many endocrine organs and 
      their axis. HIV infectivity leads to altered metabolism, poor oral intake and 
      increased prevalence of weight loss and wasting which may have a role in thyroid 
      dysfunction. Overt thyroid dysfunction occurs at similar rates as the general 
      population while subclinical disease such as nonthyroidal illness (sick euthyroid 
      syndrome), subclinical hypothyroidism and isolated low T4 levels are more 
      frequent. Moreover, HAART therapy can complicate thyroid function further through 
      drug interactions and the immune reconstitution inflammatory syndrome (IRIS). In 
      this review we report the common thyroid dysfunctions associated with HIV before 
      and after HAART therapy. We discuss presentation, diagnostic work up, treatment 
      and follow up in each condition.
FAU - Parsa, Alan A
AU  - Parsa AA
AD  - Endocrinology, Diabetes & Metabolism, Cedars-Sinai Medical Center, Los Angeles, 
      CA, USA.
FAU - Bhangoo, Amrit
AU  - Bhangoo A
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Germany
TA  - Rev Endocr Metab Disord
JT  - Reviews in endocrine & metabolic disorders
JID - 100940588
SB  - IM
MH  - Acquired Immunodeficiency Syndrome/drug therapy/metabolism/physiopathology
MH  - Antiretroviral Therapy, Highly Active
MH  - Graves Disease/drug therapy/metabolism/physiopathology
MH  - HIV Infections/*drug therapy/metabolism/*physiopathology
MH  - Humans
MH  - Hypothyroidism/metabolism/physiopathology
MH  - Models, Biological
MH  - Thyroid Diseases/metabolism/*physiopathology
MH  - Thyroid Gland/metabolism/pathology
EDAT- 2013/06/08 06:00
MHDA- 2014/01/17 06:00
CRDT- 2013/06/08 06:00
PHST- 2013/06/08 06:00 [entrez]
PHST- 2013/06/08 06:00 [pubmed]
PHST- 2014/01/17 06:00 [medline]
AID - 10.1007/s11154-013-9248-6 [doi]
PST - ppublish
SO  - Rev Endocr Metab Disord. 2013 Jun;14(2):127-31. doi: 10.1007/s11154-013-9248-6.