PMID- 23748375
OWN - NLM
STAT- MEDLINE
DCOM- 20140225
LR  - 20171116
IS  - 1932-751X (Electronic)
IS  - 1932-7501 (Linking)
VI  - 33
IP  - 4
DP  - 2013 Jul-Aug
TI  - Metabolic disease and participant age are independent predictors of response to 
      pulmonary rehabilitation.
PG  - 249-56
LID - 10.1097/HCR.0b013e31829501b7 [doi]
AB  - PURPOSE: The study aims were (1) to determine whether baseline measures-including 
      the Body Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity (BODE) 
      index; Age, Dyspnea, and Airflow Obstruction (ADO) index; physical activity; 
      comorbidities (cardiac, metabolic, or musculoskeletal disease); and the number of 
      hospitalizations over the previous 12 months-can predict responders in 6-minute 
      walk distance (6MWD) following pulmonary rehabilitation (PR) and (2) to determine 
      whether different methods in defining improvement in 6MWD affected identifying 
      responders to PR. METHODS: All participants with chronic obstructive pulmonary 
      disease who attended PR at our institution between 2004 and 2009 were evaluated. 
      A participant was classified as a responder with improvement in 6MWD (>/=25 m or >/=2 
      SD of this dataset coefficient of repeatability). RESULTS: A total of 203 
      participants (mean age, 68.2 +/- 8.7 years; mean predicted forced expiratory volume 
      in 1 second, 52.5 +/- 22.4%) were analyzed. One hundred twenty participants (59.1%) 
      had a comorbidity categorized as cardiac, metabolic, or musculoskeletal disease. 
      The binary logistic regression models showed that younger participants (P </= .015) 
      and, when using the coefficient of repeatability method (>/=60.9 m), participants 
      with metabolic disease (P = .040) were the only independent predictors of 
      response. No other measure, including participant BODE or ADO index scores, 
      contributed to either model. CONCLUSION: Identifying responders in exercise 
      capacity following PR remains difficult, with only age and participants with 
      metabolic disease identified as independent predictors.
FAU - Walsh, James R
AU  - Walsh JR
AD  - Queensland Lung Transplant Service, The Prince Charles Hospital, Brisbane, QLD 
      4032, Australia. james_walsh@health.qld.gov.au
FAU - McKeough, Zoe J
AU  - McKeough ZJ
FAU - Morris, Norman R
AU  - Morris NR
FAU - Chang, Angela T
AU  - Chang AT
FAU - Yerkovich, Stephanie T
AU  - Yerkovich ST
FAU - Seale, Helen E
AU  - Seale HE
FAU - Paratz, Jenny D
AU  - Paratz JD
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - J Cardiopulm Rehabil Prev
JT  - Journal of cardiopulmonary rehabilitation and prevention
JID - 101291247
SB  - IM
MH  - Age Factors
MH  - Aged
MH  - Body Mass Index
MH  - Exercise Therapy/*methods
MH  - Exercise Tolerance/*physiology
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Metabolic Syndrome/epidemiology/*etiology
MH  - Motor Activity/*physiology
MH  - Prevalence
MH  - Prognosis
MH  - Pulmonary Disease, Chronic Obstructive/complications/*rehabilitation
MH  - Queensland/epidemiology
MH  - Retrospective Studies
MH  - Risk Factors
EDAT- 2013/06/12 06:00
MHDA- 2014/02/26 06:00
CRDT- 2013/06/11 06:00
PHST- 2013/06/11 06:00 [entrez]
PHST- 2013/06/12 06:00 [pubmed]
PHST- 2014/02/26 06:00 [medline]
AID - 10.1097/HCR.0b013e31829501b7 [doi]
PST - ppublish
SO  - J Cardiopulm Rehabil Prev. 2013 Jul-Aug;33(4):249-56. doi: 
      10.1097/HCR.0b013e31829501b7.