PMID- 23756415
OWN - NLM
STAT- MEDLINE
DCOM- 20140610
LR  - 20151119
IS  - 1558-2035 (Electronic)
IS  - 1558-2027 (Linking)
VI  - 14
IP  - 12
DP  - 2013 Dec
TI  - Cardiac magnetic resonance for the assessment of myocardial viability: from 
      pathophysiology to clinical practice.
PG  - 862-9
LID - 10.2459/JCM.0b013e328362765e [doi]
AB  - Cardiac magnetic resonance (CMR) is commonly applied for the assessment of 
      myocardial viability in patients with ischemic ventricular dysfunction, and it 
      holds potential advantages over more traditional imaging modalities, including 
      single-photon emission computed tomography (SPECT) and dobutamine stress 
      echocardiography (DSE). CMR-based techniques for viability assessment include the 
      evaluation of transmural extent of the scar using late gadolinium enhancement 
      (LGE) images, the evaluation of end-diastolic wall thickness from resting cine 
      images and the study of inotropic reserve during low-dose dobutamine infusion. 
      During the past decade, the diffusion of the use of CMR for viability assessment 
      confirmed the clinical strengths of this modality and, at the same time, helped 
      to use old techniques with an increased level of awareness. With LGE CMR, both 
      viable and nonviable dysfunctional myocardium can be visualized in a single 
      image, allowing a direct quantification of the amount of regional viability, with 
      a significant impact on the estimation of chance for recovery. As well, studies 
      with CMR applied in the setting of ischemic heart disease allowed a better 
      understanding of the best way to apply and interpret other tests for viability 
      evaluation. For instance, it has been demonstrated that the transmural extension 
      of the scar may influence the level of concordance between SPECT and DSE in 
      assessing myocardial viability. The transmural extent of scar on LGE CMR also 
      correlates with the timing of postrevascularization recovery of systolic 
      function, with significant impact on the diagnostic accuracy of any applied 
      imaging modality.
FAU - Dellegrottaglie, Santo
AU  - Dellegrottaglie S
AD  - aDivision of Cardiology, Ospedale Medico-Chirurgico Accreditato Villa dei Fiori, 
      Acerra, Naples, Italy bZ. and M.A. Wiener Cardiovascular Institute and M.-J. and 
      H.R. Kravis Center for Cardiovascular Health, Mount Sinai Medical Center, New 
      York, NY, USA cDepartment of Advanced Biomedical Sciences, Federico II 
      University, Naples dCardiology Division, 'Cava de' Tirreni and Amalfi Coast' 
      Hospital, Heart Department, University of Salerno, Italy.
FAU - Guarini, Pasquale
AU  - Guarini P
FAU - Savarese, Gianluigi
AU  - Savarese G
FAU - Gambardella, Francesco
AU  - Gambardella F
FAU - Lo Iudice, Francesco
AU  - Lo Iudice F
FAU - Cirillo, Annapaola
AU  - Cirillo A
FAU - Vitagliano, Alice
AU  - Vitagliano A
FAU - Formisano, Tiziana
AU  - Formisano T
FAU - Pellegrino, Angela M
AU  - Pellegrino AM
FAU - Bossone, Eduardo
AU  - Bossone E
FAU - Perrone-Filardi, Pasquale
AU  - Perrone-Filardi P
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - J Cardiovasc Med (Hagerstown)
JT  - Journal of cardiovascular medicine (Hagerstown, Md.)
JID - 101259752
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Contrast Media
MH  - Gadolinium
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Myocardial Ischemia/*diagnosis/pathology/physiopathology
MH  - Myocardial Revascularization
MH  - Myocardium/*pathology
EDAT- 2013/06/13 06:00
MHDA- 2014/06/11 06:00
CRDT- 2013/06/13 06:00
PHST- 2013/06/13 06:00 [entrez]
PHST- 2013/06/13 06:00 [pubmed]
PHST- 2014/06/11 06:00 [medline]
AID - 10.2459/JCM.0b013e328362765e [doi]
PST - ppublish
SO  - J Cardiovasc Med (Hagerstown). 2013 Dec;14(12):862-9. doi: 
      10.2459/JCM.0b013e328362765e.