PMID- 23761589
OWN - NLM
STAT- MEDLINE
DCOM- 20160505
LR  - 20240109
IS  - 1941-2479 (Electronic)
IS  - 1010-5395 (Linking)
VI  - 27
IP  - 2
DP  - 2015 Mar
TI  - Rate of decline of kidney function in patients with type 2 diabetes mellitus and 
      the associated factors: a 10-year retrospective cohort study.
PG  - NP640-9
LID - 10.1177/1010539513490193 [doi]
AB  - This study examines the rate of decline of estimated glomerular filtration rate 
      (eGFR) over a 10-year period and the associated risk factors in type 2 diabetes 
      mellitus (T2DM) patients. Medical records of T2DM patients were randomly 
      selected. The rate of fall in eGFR (simplified modification of diet in renal 
      disease formula) was used as a measure of decline. Univariate and multivariate 
      analysis were performed to determine the factors associated with decline of 
      kidney function. A total of 504 patients were selected. Mean age was 57.8 +/- 9 
      years; 65.3% were females. The mean decline rate of eGFR was 0.89 +/- 2.16 
      mL/min/1.73 m(2)/y. Baseline proteinuria, glycosylated hemoglobin level, duration 
      of T2DM, and Malay race were associated with faster decline in eGFR. The expected 
      greater deterioration in kidney function in this cohort was not seen. Treatment 
      of proteinuria and glycemia should be optimized early to retard the decline in 
      kidney function in patients with T2DM.
CI  - (c) 2013 APJPH.
FAU - Foon, Tan Siow
AU  - Foon TS
AD  - University of Malaya, Kuala Lumpur, Malaysia tsiowfoon@yahoo.com.sg.
FAU - Yook Chin, Chia
AU  - Yook Chin C
AD  - Curtin University, Bentley, Western Australia, Australia.
FAU - Chinna, Karuthan
AU  - Chinna K
AD  - University of Malaya, Kuala Lumpur, Malaysia.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130611
PL  - China
TA  - Asia Pac J Public Health
JT  - Asia-Pacific journal of public health
JID - 8708538
SB  - IM
MH  - Aged
MH  - *Diabetes Mellitus, Type 2
MH  - Disease Progression
MH  - Female
MH  - Glomerular Filtration Rate/physiology
MH  - Humans
MH  - Malaysia
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Proteinuria
MH  - *Renal Insufficiency
MH  - Retrospective Studies
MH  - Risk Factors
OTO - NOTNLM
OT  - decline rate
OT  - glomerular filtration rate
OT  - retrospective cohort
OT  - risk factors
OT  - type 2 diabetes
EDAT- 2013/06/14 06:00
MHDA- 2016/05/06 06:00
CRDT- 2013/06/14 06:00
PHST- 2013/06/14 06:00 [entrez]
PHST- 2013/06/14 06:00 [pubmed]
PHST- 2016/05/06 06:00 [medline]
AID - 1010539513490193 [pii]
AID - 10.1177/1010539513490193 [doi]
PST - ppublish
SO  - Asia Pac J Public Health. 2015 Mar;27(2):NP640-9. doi: 10.1177/1010539513490193. 
      Epub 2013 Jun 11.