PMID- 23766675 OWN - NLM STAT- MEDLINE DCOM- 20130930 LR - 20211021 IS - 1537-744X (Electronic) IS - 2356-6140 (Print) IS - 1537-744X (Linking) VI - 2013 DP - 2013 TI - Autism, processing speed, and adaptive functioning in preschool children. PG - 158263 LID - 10.1155/2013/158263 [doi] LID - 158263 AB - OBJECTIVES: To study cognitive test profiles with a focus on processing speed in a representative group of preschool children with autism spectrum disorder (ASD) and relate processing speed to adaptive functioning. METHODS: Cognitive assessments were performed in 190 3.6-6.6-year-old children (164 boys and 26 girls) with ASD, using either Griffiths' developmental scales (n = 77) or the Wechsler Preschool and Primary Scale of Intelligence-Third Edition (WPPSI-III) (n = 113). Cognitive data were related to adaptive functioning as measured by Vineland Adaptive Behavior Scales (VABS). RESULTS: Cognitive profiles were characterized by low verbal skills. Low processing speed quotients (PSQs) were found in 66 (78%) of the 85 children who were able to participate in the processing speed subtests. Except for Socialization, all VABS domains (Communication, Motor Skills, Daily Living Skills, and Adaptive Behavior Composite scores) correlated significantly with PSQ. Multiple regression analysis showed that PSQ predicted 38%, 35%, 34%, and 37% of the variance for Communication, Daily Living Skills, Motor Skills, and total Adaptive Composite scores, respectively. CONCLUSION: Preschool children with ASD had uneven cognitive profiles with low verbal skills, and, relatively, even lower PSQs. Except for Socialization, adaptive functioning was predicted to a considerable degree by PSQ. FAU - Hedvall, Asa AU - Hedvall A AD - Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, Kungsgatan 12, 41119 Gothenburg, Sweden. asa.lundholm-hedvall@karolinska.se FAU - Fernell, Elisabeth AU - Fernell E FAU - Holm, Anette AU - Holm A FAU - Asberg Johnels, Jakob AU - Asberg Johnels J FAU - Gillberg, Christopher AU - Gillberg C FAU - Billstedt, Eva AU - Billstedt E LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20130520 PL - United States TA - ScientificWorldJournal JT - TheScientificWorldJournal JID - 101131163 SB - IM MH - Adaptation, Physiological MH - Autistic Disorder/diagnosis/*epidemiology/*physiopathology MH - Child MH - Child, Preschool MH - *Cognition MH - Cognition Disorders/diagnosis/*epidemiology/*physiopathology MH - *Executive Function MH - Female MH - Humans MH - Male MH - Prevalence MH - Risk Assessment MH - Sweden/epidemiology PMC - PMC3673455 EDAT- 2013/06/15 06:00 MHDA- 2013/10/01 06:00 PMCR- 2013/05/20 CRDT- 2013/06/15 06:00 PHST- 2013/02/25 00:00 [received] PHST- 2013/04/16 00:00 [accepted] PHST- 2013/06/15 06:00 [entrez] PHST- 2013/06/15 06:00 [pubmed] PHST- 2013/10/01 06:00 [medline] PHST- 2013/05/20 00:00 [pmc-release] AID - 10.1155/2013/158263 [doi] PST - epublish SO - ScientificWorldJournal. 2013 May 20;2013:158263. doi: 10.1155/2013/158263. Print 2013.