PMID- 23767197 OWN - NLM STAT- MEDLINE DCOM- 20130725 LR - 20161125 IS - 0004-5772 (Print) IS - 0004-5772 (Linking) VI - 60 DP - 2012 Nov TI - Left ventricular tissue Doppler imaging in normal adults with clinic BP of 120/80mmHg or less. PG - 16-21 AB - BACKGROUND: There is only scanty data on tissue Doppler imaging (TDI) of 'normal' adults. METHODS: Twenty eight asymptomatic adults (20-45 yrs) without cardiovascular risk factors, clinic BP < or = 120/80mmHg and normal echocardiographic examination were evaluated by tissue Doppler imaging to find normal reference values in this population. RESULTS: There was significant heterogeneity in TDI velocities and duration of different segments of left ventricle (LV). Sa and Ea velocities were lower at medial mitral annulus and middle part of interventricular septum (IVS) than at lateral mitral annulus and middle part of left ventricular lateral wall. Isovolumic contraction time (IVCT) was significantly less at lateral mitral annulus and mid part of lateral wall of LV. Isovolumic relaxation time (IVRT) was significantly less at lateral mitral annulus. Aa velocity was lower at middle part of IVS. E/Ea velocity ratio was significantly lower at lateral mitral annulus. Ea/Aa velocity ratio was always more than 1. Relatively higher values were recorded at lateral mitral annulus and mid part of left lateral wall. Myocardial performance index values were higher at mid segments than at annulus. CONCLUSION: Our data provides reference values of TDI for healthy normal adults and may help in the detection of onset of early diastolic dysfunction in this age group. FAU - Mittal, S R AU - Mittal SR AD - Department of Cardiology, St. Francis Hospital, Beawar Road, Ajmer, Rajasthan. LA - eng PT - Journal Article PL - India TA - J Assoc Physicians India JT - The Journal of the Association of Physicians of India JID - 7505585 SB - IM MH - Adult MH - Blood Pressure/physiology MH - Echocardiography, Doppler MH - Echocardiography, Doppler, Pulsed MH - Humans MH - Middle Aged MH - Mitral Valve/diagnostic imaging/physiology MH - Myocardial Contraction/physiology MH - Reference Values MH - Ventricular Function, Left/*physiology MH - Young Adult EDAT- 2013/06/19 06:00 MHDA- 2013/07/26 06:00 CRDT- 2013/06/18 06:00 PHST- 2013/06/18 06:00 [entrez] PHST- 2013/06/19 06:00 [pubmed] PHST- 2013/07/26 06:00 [medline] PST - ppublish SO - J Assoc Physicians India. 2012 Nov;60:16-21.