PMID- 23772963
OWN - NLM
STAT- MEDLINE
DCOM- 20140317
LR  - 20171116
IS  - 1520-5851 (Electronic)
IS  - 0013-936X (Linking)
VI  - 47
IP  - 14
DP  - 2013 Jul 16
TI  - Bioconcentration and biotransformation of selenite versus selenate exposed 
      periphyton and subsequent toxicity to the Mayfly Centroptilum triangulifer.
PG  - 7965-73
LID - 10.1021/es400643x [doi]
AB  - Little is known about the bioaccumulation dynamics, biotransformation processes, 
      or subsequent toxicity to consumers of dissolved selenite (SeO3) versus selenate 
      (SeO4) uptake into aquatic primary producer communities. To address these data 
      gaps, we examined SeO3 and SeO4 bioconcentration into complex freshwater 
      periphyton communities under static and static-renewal conditions. Further, we 
      explored periphyton biotransformation of Se species using X-ray absorption near 
      edge structure (XANES) spectroscopy analysis and changes in the periphyton 
      associated microbial consortium using denaturing gradient gel electrophoresis 
      (DGGE). Last, we fed differentially treated periphyton to the mayfly Centroptilum 
      triangulifer in full life cycle exposures to assess toxicity. Selenite exposed 
      periphyton readily bioconcentrated Se while, in contrast, initial periphyton 
      uptake of SeO4 was negligible, but over time periphyton [Se] increased steadily 
      in conjunction with the formation of dissolved SeO3. XANES analyses revealed that 
      both SeO3 and SeO4 treated periphyton biotransformed Se similarly with speciation 
      dominated by organo-selenide ( approximately 61%). Mayfly survival, secondary production, and 
      time to emergence were similar in both SeO3 and SeO4 treated periphyton exposures 
      with significant adverse effects at 12.8 mug g(-1) ((d.w.) secondary production) 
      and 36 mug g(-1) ((d.w.) survival and development time). Overall, dissolved 
      selenium speciation, residence time, and organisms at the base of aquatic food 
      webs appear to be the principal determinants of Se bioaccumulation and toxicity.
FAU - Conley, Justin M
AU  - Conley JM
AD  - Department of Environmental and Molecular Toxicology, North Carolina State 
      University, Raleigh, North Carolina 27695, USA.
FAU - Funk, David H
AU  - Funk DH
FAU - Hesterberg, Dean H
AU  - Hesterberg DH
FAU - Hsu, Liang-Ching
AU  - Hsu LC
FAU - Kan, Jinjun
AU  - Kan J
FAU - Liu, Yu-Ting
AU  - Liu YT
FAU - Buchwalter, David B
AU  - Buchwalter DB
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20130701
PL  - United States
TA  - Environ Sci Technol
JT  - Environmental science & technology
JID - 0213155
RN  - F6A27P4Q4R (Selenious Acid)
RN  - HV0Y51NC4J (Selenic Acid)
SB  - IM
MH  - Animals
MH  - Insecta/*drug effects/metabolism
MH  - Selenic Acid/metabolism/*toxicity
MH  - Selenious Acid/metabolism/*toxicity
EDAT- 2013/06/19 06:00
MHDA- 2014/03/19 06:00
CRDT- 2013/06/19 06:00
PHST- 2013/06/19 06:00 [entrez]
PHST- 2013/06/19 06:00 [pubmed]
PHST- 2014/03/19 06:00 [medline]
AID - 10.1021/es400643x [doi]
PST - ppublish
SO  - Environ Sci Technol. 2013 Jul 16;47(14):7965-73. doi: 10.1021/es400643x. Epub 
      2013 Jul 1.