PMID- 23780614
OWN - NLM
STAT- MEDLINE
DCOM- 20140114
LR  - 20190319
IS  - 1942-7522 (Electronic)
IS  - 0145-5613 (Linking)
VI  - 92
IP  - 6
DP  - 2013 Jun
TI  - Spindle cell lipoma of the larynx.
PG  - E9
AB  - Among the primary mesenchymal tumors of the hypopharynx and larynx, lipomas are 
      rare. Macroscopically, they often resemble a retention cyst or laryngeal nodule. 
      Spindle cell lipomas (SCLs) are an uncommon variant of lipoma. SCLs are extremely 
      rare in the larynx; as far as we know, only 4 cases have been previously 
      described in the literature. We present a new case of laryngeal SCL in a 
      65-year-old man who presented with a 1-year history of hoarseness, choking 
      spells, stridor, and dyspnea. Examination revealed the presence of a large polyp 
      on the left true vocal fold that had caused stenosis of the posterior glottis. 
      The polyp was removed endoscopically, and the patient's stridor and dyspnea 
      resolved. Histologically, the tumor was composed of bland, CD34-positive spindle 
      cells with an abundant fibrous and myxoid stroma interspersed with mature fatty 
      tissue. The patient was free of local recurrence at 2 years of follow-up.
FAU - D'Antonio, Antonio
AU  - D'Antonio A
AD  - Unit of Pathologic Anatomy, San Giovanni di Dio e Ruggi d'Aragona Hospital, 
      Salerno, Italy. ada66@inwind.it
FAU - Mottola, Giampiero
AU  - Mottola G
FAU - Caleo, Alessia
AU  - Caleo A
FAU - Addesso, Maria
AU  - Addesso M
FAU - Boscaino, Amedeo
AU  - Boscaino A
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Ear Nose Throat J
JT  - Ear, nose, & throat journal
JID - 7701817
SB  - IM
MH  - Aged
MH  - Humans
MH  - Laryngeal Neoplasms/*pathology/surgery
MH  - Lipoma/*pathology/surgery
MH  - Male
MH  - Polyps/*pathology/surgery
MH  - Rare Diseases/*pathology/surgery
EDAT- 2013/06/20 06:00
MHDA- 2014/01/15 06:00
CRDT- 2013/06/20 06:00
PHST- 2013/06/20 06:00 [entrez]
PHST- 2013/06/20 06:00 [pubmed]
PHST- 2014/01/15 06:00 [medline]
AID - 10.1177/014556131309200613 [doi]
PST - ppublish
SO  - Ear Nose Throat J. 2013 Jun;92(6):E9. doi: 10.1177/014556131309200613.