PMID- 23782653
OWN - NLM
STAT- MEDLINE
DCOM- 20131017
LR  - 20240505
IS  - 1745-6215 (Electronic)
IS  - 1745-6215 (Linking)
VI  - 14
DP  - 2013 Apr 25
TI  - Home-based reach-to-grasp training for people after stroke: study protocol for a 
      feasibility randomized controlled trial.
PG  - 109
LID - 10.1186/1745-6215-14-109 [doi]
AB  - BACKGROUND: This feasibility study is intended to assess the acceptability of 
      home-based task-specific reach-to-grasp (RTG) training for people with stroke, 
      and to gather data to inform recruitment, retention, and sample size for a 
      definitive randomized controlled trial. METHODS/DESIGN: This is to be a 
      randomized controlled feasibility trial recruiting 50 individuals with upper-limb 
      motor impairment after stroke. Participants will be recruited after discharge 
      from hospital and up to 12 months post-stroke from hospital stroke services and 
      community therapy-provider services. Participants will be assessed at baseline, 
      and then electronically randomized and allocated to group by minimization, based 
      on the time post-stroke and extent of upper-limb impairment. The intervention 
      group will receive 14 training sessions, each 1 hour long, with a physiotherapist 
      over 6 weeks and will be encouraged to practice independently for 1 hour/day to 
      give a total of 56 hours of training time per participant. Participants allocated 
      to the control group will receive arm therapy in accordance with usual care. 
      Participants will be measured at 7 weeks post-randomization, and followed-up at 3 
      and 6 months post-randomization. Primary outcome measures for assessment of arm 
      function are the Action Research Arm Test (ARAT) and Wolf Motor Function Test 
      (WMFT). Secondary measures are the Motor Activity Log, Stroke Impact Scale, Carer 
      Strain Index, and health and social care resource use. All assessments will be 
      conducted by a trained assessor blinded to treatment allocation. Recruitment, 
      adherence, withdrawals, adverse events (AEs), and completeness of data will be 
      recorded and reported. DISCUSSION: This study will determine the acceptability of 
      the intervention, the characteristics of the population recruited, recruitment 
      and retention rates, descriptive statistics of outcomes, and incidence of AEs. It 
      will provide the information needed for planning a definitive trial to test 
      home-based RTG training. TRIAL REGISTRATION ISRCTN: ISRCTN56716589.
FAU - Turton, Ailie J
AU  - Turton AJ
AD  - Department of Allied Health Professions, University of the West of England, 
      Bristol BS351NS, UK. ailie.turton@uwe.ac.uk
FAU - Cunningham, Paul
AU  - Cunningham P
FAU - Heron, Emma
AU  - Heron E
FAU - van Wijck, Frederike
AU  - van Wijck F
FAU - Sackley, Cath
AU  - Sackley C
FAU - Rogers, Chris
AU  - Rogers C
FAU - Wheatley, Keith
AU  - Wheatley K
FAU - Jowett, Sue
AU  - Jowett S
FAU - Wolf, Steven L
AU  - Wolf SL
FAU - van Vliet, Paulette
AU  - van Vliet P
LA  - eng
SI  - ISRCTN/ISRCTN56716589
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20130425
PL  - England
TA  - Trials
JT  - Trials
JID - 101263253
SB  - IM
MH  - Clinical Protocols
MH  - *Community Health Services
MH  - Disability Evaluation
MH  - England
MH  - Feasibility Studies
MH  - *Hand Strength
MH  - *Home Care Services, Hospital-Based
MH  - Humans
MH  - *Motor Activity
MH  - Patient Compliance
MH  - *Physical Therapy Modalities/adverse effects
MH  - Recovery of Function
MH  - *Research Design
MH  - Stroke/diagnosis/physiopathology
MH  - *Stroke Rehabilitation
MH  - Time Factors
MH  - Treatment Outcome
PMC - PMC3675391
EDAT- 2013/06/21 06:00
MHDA- 2013/10/18 06:00
PMCR- 2013/04/25
CRDT- 2013/06/21 06:00
PHST- 2013/02/08 00:00 [received]
PHST- 2013/03/22 00:00 [accepted]
PHST- 2013/06/21 06:00 [entrez]
PHST- 2013/06/21 06:00 [pubmed]
PHST- 2013/10/18 06:00 [medline]
PHST- 2013/04/25 00:00 [pmc-release]
AID - 1745-6215-14-109 [pii]
AID - 10.1186/1745-6215-14-109 [doi]
PST - epublish
SO  - Trials. 2013 Apr 25;14:109. doi: 10.1186/1745-6215-14-109.