PMID- 23785335
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130621
LR  - 20240322
IS  - 1664-0640 (Print)
IS  - 1664-0640 (Electronic)
IS  - 1664-0640 (Linking)
VI  - 4
DP  - 2013
TI  - BDNF and schizophrenia: from neurodevelopment to neuronal plasticity, learning, 
      and memory.
PG  - 45
LID - 10.3389/fpsyt.2013.00045 [doi]
LID - 45
AB  - Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin that has been related 
      not only to neurodevelopment and neuroprotection, but also to synapse regulation, 
      learning, and memory. Research focused on the neurobiology of schizophrenia has 
      emphasized the relevance of neurodevelopmental and neurotoxicity-related elements 
      in the pathogenesis of this disease. Research focused on the clinical features of 
      schizophrenia in the past decades has emphasized the relevance of cognitive 
      deficits of this illness, considered a core manifestation and an important 
      predictor for functional outcome. Variations in neurotrophins such as BDNF may 
      have a role as part of the molecular mechanisms underlying these processes, from 
      the neurodevelopmental alterations to the molecular mechanisms of cognitive 
      dysfunction in schizophrenia patients.
FAU - Nieto, R
AU  - Nieto R
AD  - Biomedical Neuroscience Institute, Universidad de Chile , Santiago , Chile ; 
      Clinica Psiquiatrica Universitaria, Hospital Clinico Universidad de Chile , 
      Santiago , Chile ; Laboratorio de Neurobiologia Celular y Molecular, Facultad de 
      Medicina, Universidad de Chile , Santiago , Chile.
FAU - Kukuljan, M
AU  - Kukuljan M
FAU - Silva, H
AU  - Silva H
LA  - eng
PT  - Journal Article
DEP - 20130617
PL  - Switzerland
TA  - Front Psychiatry
JT  - Frontiers in psychiatry
JID - 101545006
PMC - PMC3683823
OTO - NOTNLM
OT  - Brain-derived neurotrophic factor
OT  - cognition
OT  - learning
OT  - memory
OT  - neurodevelopment
OT  - neuroplasticity
OT  - neurotoxicity
OT  - schizophrenia
EDAT- 2013/06/21 06:00
MHDA- 2013/06/21 06:01
PMCR- 2013/06/17
CRDT- 2013/06/21 06:00
PHST- 2012/12/31 00:00 [received]
PHST- 2013/05/14 00:00 [accepted]
PHST- 2013/06/21 06:00 [entrez]
PHST- 2013/06/21 06:00 [pubmed]
PHST- 2013/06/21 06:01 [medline]
PHST- 2013/06/17 00:00 [pmc-release]
AID - 10.3389/fpsyt.2013.00045 [doi]
PST - epublish
SO  - Front Psychiatry. 2013 Jun 17;4:45. doi: 10.3389/fpsyt.2013.00045. eCollection 
      2013.