PMID- 2379397 OWN - NLM STAT- MEDLINE DCOM- 19900912 LR - 20190706 IS - 0090-3493 (Print) IS - 0090-3493 (Linking) VI - 18 IP - 8 DP - 1990 Aug TI - Hemodynamic status susceptible to slowing of heart rate during thermodilution cardiac output determination in anesthetized patients. PG - 841-4 AB - To identify hemodynamic variables that might indicate susceptibility to slowing of heart rate (HR) and to mean arterial pressure (MAP) decrease caused by cold injectate during thermodilution (TD) cardiac output determination, we measured hemodynamic variables in 32 anesthetized patients undergoing major surgery. A total of 608 cardiac output determinations were evaluated for any relationship between the magnitude of HR decreases and basal hemodynamic variables. The magnitude of HR decrease was pronounced in low cardiac index (CI), low mean pulmonary artery pressure (MPAP), and high systemic vascular resistance index (SVRI). Although there was some decrease in MAP associated with cold injectate, neither changes in SVRI nor those in the other hemodynamic variables correlated with the decreases in MAP. These results suggest that decreased CI and MPAP associated with elevated SVRI may be more susceptible to slowing of HR during cardiac output determination by TD in anesthetized patients. FAU - Nishikawa, T AU - Nishikawa T AD - Department of Anesthesiology, University of Tsukuba, Ibaraki, Japan. FAU - Dohi, S AU - Dohi S LA - eng PT - Journal Article PL - United States TA - Crit Care Med JT - Critical care medicine JID - 0355501 RN - IY9XDZ35W2 (Glucose) SB - IM MH - Adult MH - Aged MH - *Anesthesia, General MH - Blood Pressure MH - *Cardiac Output MH - Cold Temperature MH - Female MH - Glucose/administration & dosage MH - *Heart Rate MH - *Hemodynamics MH - Humans MH - Injections MH - Male MH - Middle Aged MH - *Thermodilution/methods MH - Vascular Resistance EDAT- 1990/08/01 00:00 MHDA- 1990/08/01 00:01 CRDT- 1990/08/01 00:00 PHST- 1990/08/01 00:00 [pubmed] PHST- 1990/08/01 00:01 [medline] PHST- 1990/08/01 00:00 [entrez] AID - 10.1097/00003246-199008000-00009 [doi] PST - ppublish SO - Crit Care Med. 1990 Aug;18(8):841-4. doi: 10.1097/00003246-199008000-00009.