PMID- 23796189
OWN - NLM
STAT- MEDLINE
DCOM- 20141201
LR  - 20191210
IS  - 1445-2197 (Electronic)
IS  - 1445-1433 (Linking)
VI  - 84
IP  - 4
DP  - 2014 Apr
TI  - Early experience of reinforcing the ligation of the intersphincteric fistula 
      tract procedure with a bioprosthetic graft (BioLIFT) for anal fistula.
PG  - 280-3
LID - 10.1111/ans.12242 [doi]
AB  - BACKGROUND: The BioLIFT procedure involves placing a bioprosthetic graft in the 
      intersphincteric space during the ligation of the intersphincteric fistula tract 
      (LIFT) procedure. Our study was aimed to describe our experience in the BioLIFT 
      procedure. METHODS: A review of all patients who underwent the BioLIFT procedure 
      for anal fistula from September 2011 to August 2012 was performed. Endoanal 
      ultrasonography and manometry tests were performed in all patients. RESULTS: 
      Thirteen patients with 16 fistulas underwent the BioLIFT procedure. All of them 
      had at least a seton inserted previously and the median interval to the BioLIFT 
      procedure was 20 (range, 10-41) weeks. Four patients failed a prior LIFT 
      procedure. More than half of the fistulas (56.3%) had anterior internal openings 
      and there was a female preponderance (n = 7, 53.8%). Over a median follow up of 
      26 (12-51) weeks, 11 (68.8%) fistulas had healed. The median interval between the 
      BioLIFT procedure to the diagnosis of failure was 3 (2-7) weeks. All five 
      failures had only isolated discharges at the intersphincteric wounds. Two had 
      already undergone successful lay-open fistulotomy, giving a secondary success 
      rate of 81.3%. The remaining three patients are on review. No patient developed 
      incontinent symptoms following the BioLIFT procedure and there were no 
      significant differences between the pre-procedural or post-procedural maximal 
      resting and squeeze anal manometric pressures. CONCLUSION: The BioLIFT procedure 
      can achieve a primary success rate of 68.8%. When coupled with a simple lay-open 
      fistulotomy for the subsequent intersphincteric fistula, the success rate in 
      eradicating the fistula rose to 81.3%.
CI  - (c) 2013 Royal Australasian College of Surgeons.
FAU - Tan, Ker-Kan
AU  - Tan KK
AD  - Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, New South 
      Wales, Australia.
FAU - Lee, Peter J
AU  - Lee PJ
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20130625
PL  - Australia
TA  - ANZ J Surg
JT  - ANZ journal of surgery
JID - 101086634
SB  - IM
MH  - Adult
MH  - *Bioprosthesis
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Ligation/methods
MH  - Male
MH  - Middle Aged
MH  - *Prosthesis Implantation
MH  - Rectal Fistula/*surgery
MH  - Retrospective Studies
MH  - Treatment Outcome
OTO - NOTNLM
OT  - LIFT
OT  - anal fistula
OT  - bioprosthetic mesh anorectal
EDAT- 2013/06/26 06:00
MHDA- 2014/12/15 06:00
CRDT- 2013/06/26 06:00
PHST- 2013/04/28 00:00 [accepted]
PHST- 2013/06/26 06:00 [entrez]
PHST- 2013/06/26 06:00 [pubmed]
PHST- 2014/12/15 06:00 [medline]
AID - 10.1111/ans.12242 [doi]
PST - ppublish
SO  - ANZ J Surg. 2014 Apr;84(4):280-3. doi: 10.1111/ans.12242. Epub 2013 Jun 25.