PMID- 23796809
OWN - NLM
STAT- MEDLINE
DCOM- 20140106
LR  - 20151119
IS  - 1662-2944 (Electronic)
IS  - 1421-5721 (Linking)
VI  - 44
DP  - 2013
TI  - Concept of major life-changing decisions in life course research.
PG  - 52-66
LID - 10.1159/000350389 [doi]
AB  - Chronic diseases can severely impair patients' quality of life but little 
      information is available about the long-term impact of chronic diseases. The 
      chronic nature of disease may decrease patients' psychosocial well-being, may 
      change their attitude towards life goals and influence major life-changing 
      decisions (MLCDs). Understanding of the impact on MLCDs is largely missing from 
      health outcomes research. It is potentially important in the assessment of the 
      overall burden and cumulative impact of chronic disease. This chapter reviews the 
      concepts of life events, life transition, life goals concepts and what 
      constitutes a long-term impact, essential background to this area. We also 
      describe the relationship of the concept of MLCD with the concept of cumulative 
      life course impairment. Chronic disease has long-term impact on patients' lives, 
      particularly by influencing MLCDs related to career, job, relationships, 
      education, having children and early retirement. We describe qualitative research 
      carried out in Cardiff that has sought to give more detailed insight into what 
      decisions constitute MLCDs, in patients both from dermatology and from several 
      general medical disciplines. We have also proposed the MLCD Profile to measure 
      the number of MLCDs that an individual patient may have experienced as being 
      influenced by chronic disease. Adding the domain of MLCDs to how we think about 
      the burden of disease experienced by an individual, could broaden understanding 
      of the true extent of disease impact.
CI  - Copyright (c) 2013 S. Karger AG, Basel.
FAU - Bhatti, Zaheer U
AU  - Bhatti ZU
AD  - Centre for Socioeconomic Research, Cardiff School of Pharmacy and Pharmaceutical 
      Sciences, Cardiff University, Cardiff, UK.
FAU - Salek, Sam
AU  - Salek S
FAU - Finlay, Andrew Y
AU  - Finlay AY
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20130524
PL  - Switzerland
TA  - Curr Probl Dermatol
JT  - Current problems in dermatology
JID - 0147371
SB  - IM
MH  - Adaptation, Psychological
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Chronic Disease
MH  - Cost of Illness
MH  - Cross-Sectional Studies
MH  - *Decision Making
MH  - Female
MH  - Focus Groups
MH  - Goals
MH  - Humans
MH  - *Life Change Events
MH  - Life Style
MH  - Longevity
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Skin Diseases/*psychology
MH  - Social Behavior
MH  - Surveys and Questionnaires
MH  - Young Adult
EDAT- 2013/06/26 06:00
MHDA- 2014/01/07 06:00
CRDT- 2013/06/26 06:00
PHST- 2013/06/26 06:00 [entrez]
PHST- 2013/06/26 06:00 [pubmed]
PHST- 2014/01/07 06:00 [medline]
AID - 000350389 [pii]
AID - 10.1159/000350389 [doi]
PST - ppublish
SO  - Curr Probl Dermatol. 2013;44:52-66. doi: 10.1159/000350389. Epub 2013 May 24.