PMID- 23803566
OWN - NLM
STAT- MEDLINE
DCOM- 20140422
LR  - 20160517
IS  - 2325-9574 (Print)
IS  - 2325-9574 (Linking)
VI  - 13
IP  - 1
DP  - 2014 Jan-Feb
TI  - Recurrent immune reconstitution inflammatory syndrome of tuberculous brain 
      infection in people living with HIV/AIDS: a case report.
PG  - 15-7
LID - 10.1177/2325957413488170 [doi]
AB  - HIV infection has changed the scenario of infectious disease. HIV-associated 
      immunodeficiency resulted in a wide spectrum of new opportunistic infections. 
      After introduction of antiretroviral therapy (ART), immune reconstitution 
      inflammatory syndrome (IRIS) became an important challenge in management of 10% 
      to 25% of the patients. Meta-analyses of IRIS from various reports published 
      worldwide by Monika Muller et al described 12% IRIS incidence and 15.7% IRIS 
      tuberculosis. Among IRIS tuberculosis, central nervous system involvement with 
      IRIS tuberculous meningitis forms only 7%. Only 9 cases of tuberculous brain 
      abscess is reported in patients with AIDS so far. The IRIS tuberculous brain 
      abscess is very rare, and so far only 1 case is reported as a paradoxical 
      reaction after ART initiation. Here, we report a case of recurrent IRIS 
      tuberculosis meningitis and brain abscess.
FAU - Krishnaraj, Raja
AU  - Krishnaraj R
AD  - Government Hospital of Thoracic Medicine, GST Road, Tambaram, Chennai, Tamil 
      Nadu, India.
FAU - Chokkalingam, Chandrasekar
AU  - Chokkalingam C
FAU - Krishnarajasekhar, O R
AU  - Krishnarajasekhar OR
FAU - Narayanan, Ravichandran
AU  - Narayanan R
FAU - Sadagopan, Kumar
AU  - Sadagopan K
FAU - Ayyamperumal, Mahilmaran
AU  - Ayyamperumal M
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20130626
PL  - United States
TA  - J Int Assoc Provid AIDS Care
JT  - Journal of the International Association of Providers of AIDS Care
JID - 101603896
RN  - 0 (Anti-Retroviral Agents)
RN  - 0 (Antitubercular Agents)
SB  - IM
MH  - AIDS-Related Opportunistic Infections/*immunology/*microbiology/virology
MH  - Acquired Immunodeficiency Syndrome/*immunology/microbiology
MH  - Adult
MH  - Anti-Retroviral Agents/therapeutic use
MH  - Antitubercular Agents/therapeutic use
MH  - HIV Infections/*immunology/microbiology
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*microbiology/virology
MH  - Male
MH  - Tomography, X-Ray Computed
MH  - Tuberculoma, Intracranial/immunology/*virology
OTO - NOTNLM
OT  - immune reconstitution inflammatory syndrome
OT  - opportunistic infections
OT  - paradoxical reaction
OT  - tuberculous brain abscess
EDAT- 2013/06/28 06:00
MHDA- 2014/04/23 06:00
CRDT- 2013/06/28 06:00
PHST- 2013/06/28 06:00 [entrez]
PHST- 2013/06/28 06:00 [pubmed]
PHST- 2014/04/23 06:00 [medline]
AID - 2325957413488170 [pii]
AID - 10.1177/2325957413488170 [doi]
PST - ppublish
SO  - J Int Assoc Provid AIDS Care. 2014 Jan-Feb;13(1):15-7. doi: 
      10.1177/2325957413488170. Epub 2013 Jun 26.