PMID- 23803578
OWN - NLM
STAT- MEDLINE
DCOM- 20140226
LR  - 20130812
IS  - 1872-6232 (Electronic)
IS  - 0378-3782 (Linking)
VI  - 89
IP  - 9
DP  - 2013 Sep
TI  - The effect of socioeconomic status on the language outcome of preterm infants at 
      toddler age.
PG  - 743-6
LID - S0378-3782(13)00129-1 [pii]
LID - 10.1016/j.earlhumdev.2013.05.008 [doi]
AB  - BACKGROUND: Independently, both prematurity and low socioeconomic status (SES) 
      compromise language outcome but less is known regarding the effects of low SES on 
      outcome of prior preterm infants at toddler age. AIM: To assess SES effects on 
      the language outcome of prior preterm infants at toddler age. STUDY DESIGN: 
      Retrospective chart review of infants born at </=32 weeks, matched for gestational 
      age (GA), birth weight (BW), chronic lung disease (CLD), periventricular 
      leukomalacia (PVL), right and left intraventricular hemorrhage (IVH-R, L), and 
      age at Bayley Scales of Infant Development III (BSID-III) testing. SUBJECTS: 
      Using insurance status as a proxy for SES, 65 children with private insurance 
      (P-Ins) were matched with 65 children with Medicaid-type insurance (M-Ins). 
      OUTCOME MEASURES: Bayley Scales of Infant Development-III Language Composite. 
      RESULTS: M-Ins vs. P-Ins were similar in GA, BW, and age at BSID-III testing 
      (mean 22.6 months adjusted), as well as other matched characteristics (all p >/= 
      0.16). BSID-III Language Composite scores were lower in M-Ins than P-Ins (87.9 +/- 
      11.3 vs. 101.9 +/- 13.6) with a clinically significant effect size of 0.93 (p < 
      0.001). Overall, 45% of M-Ins exhibited mild to moderate language delay compared 
      to 8% of P-Ins. Receptive and Expressive subscale scores also were lower in M-Ins 
      than in P-Ins (both p < 0.001). CONCLUSIONS: In this preterm cohort, by toddler 
      age, M-Ins was associated with lower scores on measures of overall language as 
      well as receptive and expressive language skills. Our findings, showing such an 
      early influence of SES on language outcome in a cohort matched for biomedical 
      risk, suggest that very early language interventions may be especially important 
      for low SES preterm toddlers.
CI  - Copyright (c) 2013 Elsevier Ltd. All rights reserved.
FAU - Wild, Katherine T
AU  - Wild KT
AD  - Division of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, 
      PA, USA.
FAU - Betancourt, Laura M
AU  - Betancourt LM
FAU - Brodsky, Nancy L
AU  - Brodsky NL
FAU - Hurt, Hallam
AU  - Hurt H
LA  - eng
PT  - Journal Article
DEP - 20130623
PL  - Ireland
TA  - Early Hum Dev
JT  - Early human development
JID - 7708381
SB  - IM
MH  - Case-Control Studies
MH  - Child, Preschool
MH  - Female
MH  - Humans
MH  - Infant, Newborn
MH  - Infant, Premature/*growth & development
MH  - *Language Development
MH  - Male
MH  - Retrospective Studies
MH  - *Socioeconomic Factors
OTO - NOTNLM
OT  - Bayley Scales of Infant Development III (BSID-III)
OT  - Language
OT  - Preterm infant
OT  - Socioeconomic status
EDAT- 2013/06/28 06:00
MHDA- 2014/02/27 06:00
CRDT- 2013/06/28 06:00
PHST- 2012/11/08 00:00 [received]
PHST- 2013/05/22 00:00 [revised]
PHST- 2013/05/25 00:00 [accepted]
PHST- 2013/06/28 06:00 [entrez]
PHST- 2013/06/28 06:00 [pubmed]
PHST- 2014/02/27 06:00 [medline]
AID - S0378-3782(13)00129-1 [pii]
AID - 10.1016/j.earlhumdev.2013.05.008 [doi]
PST - ppublish
SO  - Early Hum Dev. 2013 Sep;89(9):743-6. doi: 10.1016/j.earlhumdev.2013.05.008. Epub 
      2013 Jun 23.