PMID- 23804962
OWN - NLM
STAT- MEDLINE
DCOM- 20140430
LR  - 20211021
IS  - 1467-9280 (Electronic)
IS  - 0956-7976 (Print)
IS  - 0956-7976 (Linking)
VI  - 24
IP  - 8
DP  - 2013 Aug
TI  - The medial prefrontal cortex and the emergence of self-conscious emotion in 
      adolescence.
PG  - 1554-62
LID - 10.1177/0956797613475633 [doi]
AB  - In the present study, we examined the relationship between developmental 
      modulation of socioaffective brain systems and adolescents' preoccupation with 
      social evaluation. Child, adolescent, and adult participants viewed cues 
      indicating that a camera was alternately off, warming up, or projecting their 
      image to a peer during the acquisition of behavioral-, autonomic-, and 
      neural-response (functional MRI) data. Believing that a peer was actively 
      watching them was sufficient to induce self-conscious emotion that rose in 
      magnitude from childhood to adolescence and partially subsided into adulthood. 
      Autonomic arousal was uniquely heightened in adolescents. These behavioral 
      patterns were paralleled by emergent engagement of the medial prefrontal cortex 
      (MPFC) and striatum-MPFC connectivity during adolescence, which are thought to 
      promote motivated social behavior in adolescence. These findings demonstrate that 
      adolescents' self-consciousness is related to age-dependent sensitivity of brain 
      systems critical to socioaffective processes. Further, unique interactions 
      between the MPFC and striatum may provide a mechanism by which social-evaluation 
      contexts influence adolescent behavior.
FAU - Somerville, Leah H
AU  - Somerville LH
AD  - Weill Cornell Medical College, Department of Psychology, Harvard University, MA 
      02138, USA. somerville@fas.harvard.edu
FAU - Jones, Rebecca M
AU  - Jones RM
FAU - Ruberry, Erika J
AU  - Ruberry EJ
FAU - Dyke, Jonathan P
AU  - Dyke JP
FAU - Glover, Gary
AU  - Glover G
FAU - Casey, B J
AU  - Casey BJ
LA  - eng
GR  - K99 MH087813/MH/NIMH NIH HHS/United States
GR  - R00 MH087813/MH/NIMH NIH HHS/United States
GR  - K99 MH078713/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20130626
PL  - United States
TA  - Psychol Sci
JT  - Psychological science
JID - 9007542
SB  - IM
MH  - Adolescent
MH  - Adolescent Development/*physiology
MH  - Brain/physiology
MH  - Brain Mapping
MH  - Caudate Nucleus/physiology
MH  - Child
MH  - *Emotions
MH  - Female
MH  - Functional Neuroimaging
MH  - Galvanic Skin Response
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Neostriatum/*physiology
MH  - Neural Pathways/physiology
MH  - Peer Group
MH  - Prefrontal Cortex/*physiology
MH  - *Self Concept
MH  - Young Adult
PMC - PMC3742683
MID - NIHMS476098
OTO - NOTNLM
OT  - adolescence
OT  - adolescent development
OT  - brain
OT  - embarrassment
OT  - evaluation
OT  - fMRI
OT  - medial prefrontal cortex
OT  - self-consciousness
OT  - social
OT  - social cognition
EDAT- 2013/06/28 06:00
MHDA- 2014/05/03 06:00
PMCR- 2014/08/01
CRDT- 2013/06/28 06:00
PHST- 2013/06/28 06:00 [entrez]
PHST- 2013/06/28 06:00 [pubmed]
PHST- 2014/05/03 06:00 [medline]
PHST- 2014/08/01 00:00 [pmc-release]
AID - 0956797613475633 [pii]
AID - 10.1177/0956797613475633 [doi]
PST - ppublish
SO  - Psychol Sci. 2013 Aug;24(8):1554-62. doi: 10.1177/0956797613475633. Epub 2013 Jun 
      26.