PMID- 23806624 OWN - NLM STAT- MEDLINE DCOM- 20140530 LR - 20131021 IS - 1872-7123 (Electronic) IS - 0165-1781 (Linking) VI - 210 IP - 1 DP - 2013 Nov 30 TI - Association between plasma brain-derived neurotrophic factor levels and personality traits in healthy Japanese subjects. PG - 220-3 LID - S0165-1781(13)00274-6 [pii] LID - 10.1016/j.psychres.2013.05.015 [doi] AB - Although depression has been associated with decreased brain-derived neurotrophic factor (BDNF) levels for specific personality traits, there is a little information regarding the association between peripheral BDNF levels and such traits. The sample consisted of 178 healthy Japanese subjects (age range, 37.4 +/- 11.5 years). All subjects filled out the Temperament and Character Inventory (TCI). Plasma BDNF levels were measured using the enzyme-linked immunosorbent assay. A simple regression analysis revealed that plasma BDNF levels were significantly correlated with harm avoidance (r=-0.177, p=0.018) and self-directedness scores (r=0.165, p=0.028). Our findings suggest that plasma BDNF levels are associated with depression-related personality traits. CI - Copyright (c) 2013 Elsevier Ireland Ltd. All rights reserved. FAU - Yasui-Furukori, Norio AU - Yasui-Furukori N AD - Department of Neuropsychiatry, Hirosaki University School of Medicine, Hirosaki 036-8562, Japan. Electronic address: yasufuru@cc.hirosaki-u.ac.jp. FAU - Tsuchimine, Shoko AU - Tsuchimine S FAU - Kaneda, Ayako AU - Kaneda A FAU - Sugawara, Norio AU - Sugawara N FAU - Ishioka, Masamichi AU - Ishioka M FAU - Kaneko, Sunao AU - Kaneko S LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20130624 PL - Ireland TA - Psychiatry Res JT - Psychiatry research JID - 7911385 RN - 0 (Brain-Derived Neurotrophic Factor) SB - IM MH - Adult MH - Brain-Derived Neurotrophic Factor/*blood MH - Depression/blood MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Humans MH - Japan MH - Male MH - Middle Aged MH - *Personality MH - Personality Inventory MH - Regression Analysis OTO - NOTNLM OT - Brain-derived neurotrophic factor OT - Personality OT - Plasma OT - Temperament and Character Inventory EDAT- 2013/06/29 06:00 MHDA- 2014/05/31 06:00 CRDT- 2013/06/29 06:00 PHST- 2011/08/08 00:00 [received] PHST- 2013/05/04 00:00 [revised] PHST- 2013/05/07 00:00 [accepted] PHST- 2013/06/29 06:00 [entrez] PHST- 2013/06/29 06:00 [pubmed] PHST- 2014/05/31 06:00 [medline] AID - S0165-1781(13)00274-6 [pii] AID - 10.1016/j.psychres.2013.05.015 [doi] PST - ppublish SO - Psychiatry Res. 2013 Nov 30;210(1):220-3. doi: 10.1016/j.psychres.2013.05.015. Epub 2013 Jun 24.