PMID- 23806679 OWN - NLM STAT- MEDLINE DCOM- 20140220 LR - 20191210 IS - 1872-7565 (Electronic) IS - 0169-2607 (Linking) VI - 111 IP - 3 DP - 2013 Sep TI - Adaptive network based on fuzzy inference system for equilibrated urea concentration prediction. PG - 578-91 LID - S0169-2607(13)00169-7 [pii] LID - 10.1016/j.cmpb.2013.05.012 [doi] AB - Post-dialysis urea rebound (PDUR) has been attributed mostly to redistribution of urea from different compartments, which is determined by variations in regional blood flows and transcellular urea mass transfer coefficients. PDUR occurs after 30-90min of short or standard hemodialysis (HD) sessions and after 60min in long 8-h HD sessions, which is inconvenient. This paper presents adaptive network based on fuzzy inference system (ANFIS) for predicting intradialytic (Cint) and post-dialysis urea concentrations (Cpost) in order to predict the equilibrated (Ceq) urea concentrations without any blood sampling from dialysis patients. The accuracy of the developed system was prospectively compared with other traditional methods for predicting equilibrated urea (Ceq), post dialysis urea rebound (PDUR) and equilibrated dialysis dose (eKt/V). This comparison is done based on root mean squares error (RMSE), normalized mean square error (NRMSE), and mean absolute percentage error (MAPE). The ANFIS predictor for Ceq achieved mean RMSE values of 0.3654 and 0.4920 for training and testing, respectively. The statistical analysis demonstrated that there is no statistically significant difference found between the predicted and the measured values. The percentage of MAE and RMSE for testing phase is 0.63% and 0.96%, respectively. CI - Copyright (c) 2013 Elsevier Ireland Ltd. All rights reserved. FAU - Azar, Ahmad Taher AU - Azar AT AD - Faculty of computers and Information, Benha university, Benha, Egypt. ahmad_T_azar@ieee.org LA - eng PT - Journal Article DEP - 20130624 PL - Ireland TA - Comput Methods Programs Biomed JT - Computer methods and programs in biomedicine JID - 8506513 SB - IM MH - Blood Urea Nitrogen MH - *Fuzzy Logic MH - *Hemodynamics MH - Humans MH - Neural Networks, Computer OTO - NOTNLM OT - Adaptive neuro-fuzzy inference system (ANFIS) OT - Equilibrated dialysis adequacy ((e)Kt/V) OT - Equilibrated urea concentration (C(eq)) OT - Intradialytic urea concentration (C(int)) OT - Post dialysis urea rebound (PDUR) OT - Takagi-Sugeno-Kang (TSK) fuzzy inference system EDAT- 2013/06/29 06:00 MHDA- 2014/02/22 06:00 CRDT- 2013/06/29 06:00 PHST- 2012/11/16 00:00 [received] PHST- 2013/04/05 00:00 [revised] PHST- 2013/05/23 00:00 [accepted] PHST- 2013/06/29 06:00 [entrez] PHST- 2013/06/29 06:00 [pubmed] PHST- 2014/02/22 06:00 [medline] AID - S0169-2607(13)00169-7 [pii] AID - 10.1016/j.cmpb.2013.05.012 [doi] PST - ppublish SO - Comput Methods Programs Biomed. 2013 Sep;111(3):578-91. doi: 10.1016/j.cmpb.2013.05.012. Epub 2013 Jun 24.