PMID- 23808870
OWN - NLM
STAT- MEDLINE
DCOM- 20141208
LR  - 20171116
IS  - 1365-277X (Electronic)
IS  - 0952-3871 (Linking)
VI  - 27 Suppl 2
DP  - 2014 Apr
TI  - Relationship between childhood obesity cut-offs and metabolic and vascular 
      comorbidities: comparative analysis of three growth standards.
PG  - 75-83
LID - 10.1111/jhn.12140 [doi]
AB  - BACKGROUND: To compare the association between metabolic and vascular 
      comorbidities and the body mass (BMI)-for-age cut-off criteria from three growth 
      standards [Centers for Disease Control and Prevention (CDC), 2000; World Health 
      Organization (WHO), 2007; Spanish Reference Criteria (Carrascosa Lezcano et al., 
      2008)] that are used to define being overweight and obese in childhood. METHODS: 
      A prospective study was conducted in 137 children (aged 8-16 years). Based on 
      BMI-for-age Z-scores according to WHO cut-offs, 59 participants were obese, 35 
      were overweight and 43 were normal-weight. All participating children were 
      subsequently reclassified applying the CDC and Spanish Reference Criteria. Blood 
      pressure (BP), biochemical variables and vascular parameters (stiffness and 
      intima-media thickness) were analysed. RESULTS: According to WHO and CDC 
      references, 48% and 43% of the children, respectively, were categorised as obese, 
      whereas 16% were considered as obese using the Spanish Reference Criteria. 
      Applying WHO criteria, obese children showed significantly higher levels of 
      insulin, homeostasis model assessment index and most vascular parameters, as well 
      as lower high-density lipoprotein (HDL)-cholesterol than overweight children. 
      Moreover, overweight children showed higher BP, insulin and uric acid, and lower 
      HDL-cholesterol than normal weight children. The CDC criteria yielded similar 
      results, although with fewer differences between obese and overweight children. 
      Applying Spanish criteria, the differences between obese and overweight children 
      disappeared. CONCLUSIONS: WHO and CDC BMI-for-age references and cut-offs are 
      useful for defining obesity and being overweight in children because they clearly 
      identify metabolic and vascular comorbidities. The Spanish Reference Criteria 
      underdiagnose obesity because overweight children show comorbidities typical of 
      the obese.
CI  - (c) 2013 The British Dietetic Association Ltd.
FAU - Martinez-Costa, C
AU  - Martinez-Costa C
AD  - Pediatric Gastroenterology and Nutrition Unit, Department of Pediatrics, Hospital 
      Clinico Universitario of Valencia, University of Valencia, Valencia, Spain.
FAU - Nunez, F
AU  - Nunez F
FAU - Montal, A
AU  - Montal A
FAU - Brines, J
AU  - Brines J
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20130627
PL  - England
TA  - J Hum Nutr Diet
JT  - Journal of human nutrition and dietetics : the official journal of the British 
      Dietetic Association
JID - 8904840
RN  - 0 (Blood Glucose)
RN  - 0 (Cholesterol, HDL)
RN  - 0 (Cholesterol, LDL)
RN  - 0 (Insulin)
RN  - 0 (Triglycerides)
SB  - IM
MH  - Adolescent
MH  - Blood Glucose/metabolism
MH  - Blood Pressure
MH  - Body Height
MH  - Body Mass Index
MH  - Body Weight
MH  - Cardiovascular Diseases/blood/diagnosis/*epidemiology
MH  - Carotid Intima-Media Thickness
MH  - Child
MH  - Cholesterol, HDL/blood
MH  - Cholesterol, LDL/blood
MH  - Comorbidity
MH  - Female
MH  - Humans
MH  - Insulin/blood
MH  - Male
MH  - Metabolic Syndrome/blood/diagnosis/*epidemiology
MH  - Nutrition Assessment
MH  - Nutritional Status
MH  - Overweight/blood/diagnosis/*epidemiology
MH  - Pediatric Obesity/blood/diagnosis/*epidemiology
MH  - Prospective Studies
MH  - Spain/epidemiology
MH  - Triglycerides/blood
OTO - NOTNLM
OT  - body mass index
OT  - childhood obesity
OT  - obesity comorbidities
OT  - obesity diagnosis
OT  - reference growth curves
EDAT- 2013/07/03 06:00
MHDA- 2014/12/15 06:00
CRDT- 2013/07/02 06:00
PHST- 2013/07/02 06:00 [entrez]
PHST- 2013/07/03 06:00 [pubmed]
PHST- 2014/12/15 06:00 [medline]
AID - 10.1111/jhn.12140 [doi]
PST - ppublish
SO  - J Hum Nutr Diet. 2014 Apr;27 Suppl 2:75-83. doi: 10.1111/jhn.12140. Epub 2013 Jun 
      27.