PMID- 23818215
OWN - NLM
STAT- MEDLINE
DCOM- 20151223
LR  - 20220311
IS  - 1873-1953 (Electronic)
IS  - 1474-5151 (Linking)
VI  - 13
IP  - 4
DP  - 2014 Aug
TI  - Relationship of health-related quality of life with fatigue and exercise capacity 
      in patients with coronary artery disease.
PG  - 338-44
LID - 10.1177/1474515113496942 [doi]
AB  - OBJECTIVE: The study objective was to evaluate the relationship of health-related 
      quality of life (HRQoL) with fatigue and exercise capacity in coronary artery 
      disease (CAD) patients. METHODS: A total of 1072 consecutive CAD patients on 
      admission to a cardiac rehabilitation program were evaluated for HRQoL (36-item 
      Short Form Medical Outcome Questionnaire; SF-36), body mass index, clinical 
      characteristics (New York Heart Association (NYHA) class, angina pectoris class, 
      coronary interventions, treatment with beta blockers, hypertension and diabetes), 
      symptoms of depression and anxiety (Hospital Anxiety and Depression Scale), 
      fatigue (Multidimensional Fatigue Inventory-20; MFI-20), and exercise capacity 
      (bicycle ergometer test). RESULTS: In univariate regression analyses lower scores 
      on all SF-36 domains were associated with greater scores on all MFI-20 subscales. 
      Exercise capacity was associated with all SF-36 domains, except for social 
      functioning and mental health domains. In multivariate regression analyses, after 
      adjusting for age, gender, body mass index, NYHA class, angina pectoris class, 
      hypertension, diabetes, coronary interventions, treatment with betablockers, and 
      symptoms of depression and anxiety, greater limitation due to physical and due to 
      emotional problems, poor social functioning, decreased energy/vitality, worse 
      general health perception, reduced mental component summary and lower global 
      SF-36 score were independently associated with higher MFI-20 general fatigue 
      score. Reduced physical functioning, greater pain, and reduced physical component 
      summary SF-36 scores were associated with greater MFI-20 physical fatigue score. 
      Lower SF-36 mental health score was associated, with greater MFI-20 mental 
      fatigue score. CONCLUSION: In CAD patients undergoing rehabilitation, poor HRQoL 
      is associated with greater fatigue and decreased exercise capacity independently 
      from mental distress and CAD severity score.
CI  - (c) The European Society of Cardiology 2013.
FAU - Staniute, Margarita
AU  - Staniute M
AD  - Behavioral Medicine Institute, Lithuanian University of Health Sciences, 
      Lithuania mstaniute@ktl.mii.lt.
FAU - Bunevicius, Adomas
AU  - Bunevicius A
AD  - Behavioral Medicine Institute, Lithuanian University of Health Sciences, 
      Lithuania.
FAU - Brozaitiene, Julija
AU  - Brozaitiene J
AD  - Behavioral Medicine Institute, Lithuanian University of Health Sciences, 
      Lithuania.
FAU - Bunevicius, Robertas
AU  - Bunevicius R
AD  - Behavioral Medicine Institute, Lithuanian University of Health Sciences, 
      Lithuania.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130701
PL  - England
TA  - Eur J Cardiovasc Nurs
JT  - European journal of cardiovascular nursing
JID - 101128793
SB  - IM
MH  - Aged
MH  - Comorbidity
MH  - Coronary Artery Disease/epidemiology/physiopathology/*rehabilitation
MH  - *Exercise Tolerance
MH  - Fatigue/*epidemiology
MH  - Female
MH  - Health Status Indicators
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Quality of Life
MH  - Severity of Illness Index
OTO - NOTNLM
OT  - Health-related quality of life
OT  - coronary artery disease
OT  - exercise capacity
OT  - fatigue
EDAT- 2013/07/03 06:00
MHDA- 2015/12/24 06:00
CRDT- 2013/07/03 06:00
PHST- 2013/03/07 00:00 [received]
PHST- 2013/06/17 00:00 [accepted]
PHST- 2013/07/03 06:00 [entrez]
PHST- 2013/07/03 06:00 [pubmed]
PHST- 2015/12/24 06:00 [medline]
AID - 1474515113496942 [pii]
AID - 10.1177/1474515113496942 [doi]
PST - ppublish
SO  - Eur J Cardiovasc Nurs. 2014 Aug;13(4):338-44. doi: 10.1177/1474515113496942. Epub 
      2013 Jul 1.