PMID- 23823988 OWN - NLM STAT- MEDLINE DCOM- 20131224 LR - 20231206 IS - 1689-0035 (Electronic) IS - 0065-1400 (Linking) VI - 73 IP - 2 DP - 2013 TI - Effect of Val66Met polymorphism in BDNF on attentional bias in an extroverted Chinese Han population. PG - 280-8 LID - 1936 [pii] LID - 10.55782/ane-2013-1936 [doi] AB - Studies have indicated that a functional polymorphism (Val66Met) in a brain-derived neurotrophic factor (BDNF) gene can influences human cognitive functions and mood disorders. In this study, we examined associations of BDNF Val66Met with attentional bias and personality in an unaffected population. The results showed that BDNF Val66Met was significantly associated with attentional disengagement for positive cueing words in extraverts. Moreover, there was a positive correlation between the dosages of Met allele and attentional disengagement, however, we did not observe any significant influences of BDNF Val66Met on personality traits. These preliminary results indicate that the individual differences in attentional bias for positive words are partially underpinned by BDNF. FAU - Gong, Pingyuan AU - Gong P AD - College of Medicine, Henan University of Science and Technology, Luoyang, China. gpy1026@163.com. FAU - Xi, Shoumin AU - Xi S FAU - Li, She AU - Li S FAU - Cao, Guochang AU - Cao G FAU - Zhang, Peizhe AU - Zhang P FAU - Shen, Guomin AU - Shen G FAU - Zhang, Fuchang AU - Zhang F FAU - Shen, Yan AU - Shen Y FAU - Ma, Hua AU - Ma H LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Poland TA - Acta Neurobiol Exp (Wars) JT - Acta neurobiologiae experimentalis JID - 1246675 RN - 0 (Brain-Derived Neurotrophic Factor) RN - AE28F7PNPL (Methionine) RN - HG18B9YRS7 (Valine) SB - IM MH - Asian People/ethnology/genetics MH - Attention/*physiology MH - *Bias MH - Brain-Derived Neurotrophic Factor/*genetics MH - Female MH - Genetic Association Studies MH - Genotype MH - Humans MH - Male MH - Methionine/genetics MH - Neuropsychological Tests MH - Personality/*genetics MH - Personality Inventory MH - Polymorphism, Genetic/*genetics MH - Surveys and Questionnaires MH - Valine/genetics MH - Young Adult EDAT- 2013/07/05 06:00 MHDA- 2013/12/25 06:00 CRDT- 2013/07/05 06:00 PHST- 2013/07/05 06:00 [entrez] PHST- 2013/07/05 06:00 [pubmed] PHST- 2013/12/25 06:00 [medline] AID - 1936 [pii] AID - 10.55782/ane-2013-1936 [doi] PST - ppublish SO - Acta Neurobiol Exp (Wars). 2013;73(2):280-8. doi: 10.55782/ane-2013-1936.