PMID- 2382614
OWN - NLM
STAT- MEDLINE
DCOM- 19900907
LR  - 20190626
IS  - 0002-8703 (Print)
IS  - 0002-8703 (Linking)
VI  - 120
IP  - 2
DP  - 1990 Aug
TI  - Factors influencing the outcome of balloon aortic valvuloplasty in the elderly.
PG  - 373-80
AB  - This study describes the short- and long-term outcome of 44 consecutive 
      percutaneous balloon aortic valvuloplasty procedures performed in 42 elderly 
      patients (age 77.8 +/- 7 years) with calcific aortic stenosis. The initial 
      success rate was 95%, with the peak aortic valve pressure gradient declining from 
      a mean of 82 +/- 32 mm Hg to 44 +/- 23 mm Hg and aortic valve area increasing 
      from a mean of 0.59 +/- 0.15 cm2 to 0.83 +/- 0.40 cm2. One procedure-related 
      death occurred and an additional three patients died less than or equal to 30 
      days after balloon aortic valvuloplasty. These patients all had New York Heart 
      Association (NYHA) class IV heart failure symptoms prior to the procedure and 
      their mean left ventricular ejection fraction (LVEF) (28 +/- 7%) was lower than 
      that of hospital survivors (52 +/- 13%) (as was their ratio of left ventricular 
      [LV] wall thickness-to-cavity ratio [0.50 +/- 0.10 versus 0.70 +/- 0.15]). At the 
      time of hospital discharge after valvuloplasty, 76% of patients were asymptomatic 
      or markedly improved (NYHA class I or II). After a mean follow-up of 15.5 months 
      (range 2 to 26 months), however, 10 patients had died and 15 had undergone aortic 
      valve replacement for recurrence of NYHA class III or IV symptoms. The adjusted 
      1- and 2-year survivals were 0.68 and 0.62, respectively, and adjusted 2-year 
      event-free survival was 0.25. Proportional hazard regression analysis indicated 
      that LVEF less than 40% was the only variable affecting survival (p less than 
      0.01) and was a possible indicator of event-free survival (p = 0.07).(ABSTRACT 
      TRUNCATED AT 250 WORDS)
FAU - Rodriguez, A R
AU  - Rodriguez AR
AD  - Department of Medicine, Baylor College of Medicine, Houston, TX.
FAU - Kleiman, N S
AU  - Kleiman NS
FAU - Minor, S T
AU  - Minor ST
FAU - Zoghbi, W A
AU  - Zoghbi WA
FAU - West, M S
AU  - West MS
FAU - DeFelice, C A
AU  - DeFelice CA
FAU - Samuels, D A
AU  - Samuels DA
FAU - Cashion, R
AU  - Cashion R
FAU - Pickett, J D
AU  - Pickett JD
FAU - Lewis, J M
AU  - Lewis JM
AU  - et al.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Am Heart J
JT  - American heart journal
JID - 0370465
SB  - IM
MH  - Aged
MH  - Aortic Valve Stenosis/mortality/physiopathology/*therapy
MH  - *Catheterization
MH  - Heart Valve Prosthesis
MH  - Hemodynamics
MH  - Hospitalization
MH  - Humans
MH  - Prognosis
MH  - Recurrence
MH  - Reoperation
MH  - Survival Analysis
EDAT- 1990/08/01 00:00
MHDA- 1990/08/01 00:01
CRDT- 1990/08/01 00:00
PHST- 1990/08/01 00:00 [pubmed]
PHST- 1990/08/01 00:01 [medline]
PHST- 1990/08/01 00:00 [entrez]
AID - 0002-8703(90)90082-9 [pii]
AID - 10.1016/0002-8703(90)90082-9 [doi]
PST - ppublish
SO  - Am Heart J. 1990 Aug;120(2):373-80. doi: 10.1016/0002-8703(90)90082-9.