PMID- 23831000
OWN - NLM
STAT- MEDLINE
DCOM- 20131022
LR  - 20130716
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1302
DP  - 2013 Aug 9
TI  - Ultrasound-assisted dispersive liquid-liquid microextraction plus simultaneous 
      silylation for rapid determination of salicylate and benzophenone-type 
      ultraviolet filters in aqueous samples.
PG  - 20-7
LID - S0021-9673(13)00912-6 [pii]
LID - 10.1016/j.chroma.2013.06.017 [doi]
AB  - A rapid procedure, using minimal amounts of solvent, for the reliable 
      determination of five salicylate and benzophenone-type ultraviolet (UV) filters: 
      ethylhexyl salicylate (EHS), 3,3,5-trimethyl-cyclohexyl salicylate (HMS), 
      2-hydroxy-4-methoxybenzophenone (BP-3), 2,4-dihydroxy-benzophenone (BP-1) and 
      2,2'-dihydroxy-4-methoxybenzophenone (BP-8), in aqueous samples is described. The 
      method involves an ultrasound-assisted dispersive liquid-liquid microextraction 
      (UA-DLLME) plus simultaneous silylation prior to their determination by gas 
      chromatography-mass spectrometry (GC-MS). The parameters affecting the extraction 
      and derivatization efficiency of the target UV filters from aqueous samples were 
      systematically investigated and the conditions optimized. The optimal silylation 
      and extraction conditions involved the rapid injection of a mixture of 750muL of 
      acetone (as a dispersant), 15muL of tetrachloroethylene (as an extractant), and 
      20muL of BSTFA (as a derivatizing agent) into a 10-mL volume of aqueous samples 
      (pH 7.0) containing 0.5g of sodium chloride in a glass tube with a conical 
      bottom. After ultrasonication for 2.0min and centrifugation at 5000rpm (10min), 
      the sedimented phase 5.0muL was directly introduced into the GC-MS. The limits of 
      quantitation (LOQs) were less than 6ng/L. The precision for these analytes, as 
      indicated by the relative standard deviations (RSDs), was less than 9% for both 
      intra- and inter-day analysis. Accuracy, expressed as the mean extraction 
      recovery, was between 74 and 92%. The method was then applied to environmental 
      aqueous samples, using a standard addition method, showing the occurrence of BP-3 
      in samples of both river water and municipal wastewater treatment plant (MWTP) 
      effluents.
CI  - Copyright (c) 2013 Elsevier B.V. All rights reserved.
FAU - Wu, Jen-Wen
AU  - Wu JW
AD  - Department of Chemistry, National Central University, Chung-Li 320, Taiwan.
FAU - Chen, Hsin-Chang
AU  - Chen HC
FAU - Ding, Wang-Hsien
AU  - Ding WH
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130618
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Benzophenones)
RN  - 0 (Salicylates)
SB  - IM
MH  - Benzophenones/*analysis
MH  - Filtration/methods
MH  - Liquid Phase Microextraction/*methods
MH  - Molecular Structure
MH  - Salicylates/*analysis
OTO - NOTNLM
OT  - GC-MS
OT  - Organic UV filters
OT  - Simultaneous silylation
OT  - Ultrasound-assisted dispersive liquid-liquid microextraction
OT  - Water sample analysis
EDAT- 2013/07/09 06:00
MHDA- 2013/10/23 06:00
CRDT- 2013/07/09 06:00
PHST- 2013/04/10 00:00 [received]
PHST- 2013/06/10 00:00 [revised]
PHST- 2013/06/11 00:00 [accepted]
PHST- 2013/07/09 06:00 [entrez]
PHST- 2013/07/09 06:00 [pubmed]
PHST- 2013/10/23 06:00 [medline]
AID - S0021-9673(13)00912-6 [pii]
AID - 10.1016/j.chroma.2013.06.017 [doi]
PST - ppublish
SO  - J Chromatogr A. 2013 Aug 9;1302:20-7. doi: 10.1016/j.chroma.2013.06.017. Epub 
      2013 Jun 18.