PMID- 23831267
OWN - NLM
STAT- MEDLINE
DCOM- 20140320
LR  - 20201226
IS  - 1471-4981 (Electronic)
IS  - 1471-4906 (Linking)
VI  - 34
IP  - 9
DP  - 2013 Sep
TI  - Inflammatory dendritic cells in mice and humans.
PG  - 440-5
LID - S1471-4906(13)00091-4 [pii]
LID - 10.1016/j.it.2013.06.001 [doi]
AB  - Dendritic cells (DCs) are a heterogeneous population of professional 
      antigen-presenting cells. Several murine DC subsets have been identified that 
      differ in their phenotype and functional properties. In the steady state, DC 
      precursors originating from the bone marrow give rise to lymphoid-organ-resident 
      DCs and to migratory tissue DCs. During inflammation, an additional DC subset has 
      been described, so-called inflammatory DCs (infDCs), which differentiate from 
      monocytes recruited to the site of inflammation. Here, we review recent work on 
      the development and functions of murine infDCs. We also examine the criteria that 
      define infDCs. Finally, we discuss the characterization of human infDCs and their 
      potential role in inflammatory diseases.
CI  - Copyright (c) 2013 Elsevier Ltd. All rights reserved.
FAU - Segura, Elodie
AU  - Segura E
AD  - INSERM U932, 26 rue d'Ulm, 75005 Paris, France; Institut Curie, Section 
      Recherche, 26 rue d'Ulm, 75005 Paris, France. Electronic address: 
      elodie.segura@curie.fr.
FAU - Amigorena, Sebastian
AU  - Amigorena S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20130704
PL  - England
TA  - Trends Immunol
JT  - Trends in immunology
JID - 100966032
SB  - IM
MH  - Animals
MH  - Cell Differentiation/immunology
MH  - Dendritic Cells/cytology/*immunology
MH  - Humans
MH  - Inflammation/*immunology
MH  - Lymphocyte Activation/immunology
MH  - Mice
MH  - Monocytes/cytology/immunology
OTO - NOTNLM
OT  - dendritic cells
OT  - inflammation
EDAT- 2013/07/09 06:00
MHDA- 2014/03/22 06:00
CRDT- 2013/07/09 06:00
PHST- 2013/03/25 00:00 [received]
PHST- 2013/05/21 00:00 [revised]
PHST- 2013/06/05 00:00 [accepted]
PHST- 2013/07/09 06:00 [entrez]
PHST- 2013/07/09 06:00 [pubmed]
PHST- 2014/03/22 06:00 [medline]
AID - S1471-4906(13)00091-4 [pii]
AID - 10.1016/j.it.2013.06.001 [doi]
PST - ppublish
SO  - Trends Immunol. 2013 Sep;34(9):440-5. doi: 10.1016/j.it.2013.06.001. Epub 2013 
      Jul 4.