PMID- 23833947
OWN - NLM
STAT- MEDLINE
DCOM- 20160202
LR  - 20190318
IS  - 0513-4870 (Print)
IS  - 0513-4870 (Linking)
VI  - 48
IP  - 4
DP  - 2013 Apr
TI  - [Synthesis and bioactivity of the folate receptor targeted 
      gamma-cyclodextrin-folate inclusion-coated CdSe/ZnS quantum dots].
PG  - 566-72
AB  - The gamma-cyclodextrin-folate (gamma-CD/FA) inclusion-coated CdSe/ZnS quantum 
      dots (QDs) with folate-receptor (FR) targeted were synthesized by simple and 
      convenient sonochemical method. The products were studied using Fourier transform 
      infrared (FTIR), proton nuclear magnetic resonance (1H NMR), utraviolet-visible 
      spectrometry (UV-vis), fluorescence spectrum and transmission electron 
      micrographs (TEM). The results showed that the gamma-CD/FA-coated CdSe/ZnS QDs 
      not only have good monodispersity and smaller size, but also have good optical 
      performance, such as higher quantum yield (QY) and a long fluorescence lifetime. 
      The cytotoxicity experiments showed that the gamma-CD/FA-coated CdSe/ZnS QDs have 
      lower cytotoxicity and could more effectively enter cancer cells with FR 
      over-expression. The QDs with 4-5 nm in diameter were relatively easy to enter 
      the cell and to be removed through kidneys, so it is more suitable for biomedical 
      applications for bioprobes and bioimaging.
FAU - Zhao, Mei-Xia
AU  - Zhao MX
AD  - Key Laboratory of Natural Medicine and Immune Engineering, Henan University, 
      Kaifeng 475004, China. zhaomeixia2011@henu.edu.cn
FAU - Li, Yang
AU  - Li Y
FAU - Wang, Chao-Jie
AU  - Wang CJ
LA  - chi
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Yao Xue Xue Bao
JT  - Yao xue xue bao = Acta pharmaceutica Sinica
JID - 21710340R
RN  - 0 (Cadmium Compounds)
RN  - 0 (Folate Receptor 1)
RN  - 0 (Selenium Compounds)
RN  - 0 (Sulfides)
RN  - 0 (Zinc Compounds)
RN  - 0 (gamma-Cyclodextrins)
RN  - 935E97BOY8 (Folic Acid)
RN  - A7F646JC5C (cadmium selenide)
RN  - KPS085631O (zinc sulfide)
RN  - KZJ0BYZ5VA (gamma-cyclodextrin)
SB  - IM
MH  - *Cadmium Compounds/chemical synthesis/chemistry/metabolism/toxicity
MH  - Cell Survival/drug effects
MH  - Folate Receptor 1/*chemistry
MH  - Folic Acid/*chemistry
MH  - HeLa Cells
MH  - Hep G2 Cells
MH  - Humans
MH  - Magnetic Resonance Spectroscopy
MH  - Microscopy, Electron, Transmission
MH  - Molecular Imaging/methods
MH  - *Quantum Dots/chemistry/metabolism/toxicity
MH  - *Selenium Compounds/chemical synthesis/chemistry/metabolism/toxicity
MH  - Spectrophotometry, Ultraviolet
MH  - Spectroscopy, Fourier Transform Infrared
MH  - *Sulfides/chemical synthesis/chemistry/metabolism/toxicity
MH  - *Zinc Compounds/chemical synthesis/chemistry/metabolism/toxicity
MH  - gamma-Cyclodextrins/*chemistry
EDAT- 2013/07/10 06:00
MHDA- 2016/02/03 06:00
CRDT- 2013/07/10 06:00
PHST- 2013/07/10 06:00 [entrez]
PHST- 2013/07/10 06:00 [pubmed]
PHST- 2016/02/03 06:00 [medline]
PST - ppublish
SO  - Yao Xue Xue Bao. 2013 Apr;48(4):566-72.