PMID- 23834132
OWN - NLM
STAT- MEDLINE
DCOM- 20150526
LR  - 20181023
IS  - 1300-7475 (Print)
IS  - 1300-7475 (Linking)
VI  - 23
IP  - 4
DP  - 2013 Jul-Aug
TI  - Effects of topical sprays on allergy-induced nasal obstruction in children.
PG  - 217-24
LID - kbbihtisas.2013.27132 [pii]
LID - 10.5606/kbbihtisas.2013.27132 [doi]
AB  - OBJECTIVES: This study aims to evaluate the efficacy of mometasone furoate nasal 
      spray, intranasal azelastine, and isotonic sea water nasal spray in the 
      management of allergy-induced nasal obstruction. PATIENTS AND METHODS: Between 
      October 2007 and August 2008 60 patients (37 males, 23 females; mean age 9.8+/-2.6 
      years; range 7 to 16 years) with a history of allergic rhinitis were included in 
      the study. Laboratory assays including the skin prick test, nasal smear, 
      phadiatop, total immunoglobulin E (IgE), and complete blood count test were 
      performed. The patients were classified into three groups including 20 in each, 
      according to the topical treatment administered. Patients in group 1 received 
      azelastine, group 2 received mometasone furoate nasal spray, and group 3 received 
      isotonic sea water nasal spray. Nasal passage volume was calculated using an 
      acoustic rhinometry device. RESULTS: Azelastine and mometasone furoate decreased 
      nasal congestion and increased nasal cavity volume more effectively, compared to 
      isotonic sea water nasal spray. CONCLUSION: Mometasone furoate and azelastine 
      which decrease nasal congestion and increase nasal volume are effective in the 
      management of allergic rhinitis in children.
FAU - Yasar, Mehmet
AU  - Yasar M
AD  - Department of Otolaryngology, Kayseri Training and Research Hospital, 38010 
      Kayseri, Turkey. drmyasar@hotmail.com
FAU - Uysal, Ismail Onder
AU  - Uysal IO
FAU - Altuntas, Emine Elif
AU  - Altuntas EE
FAU - Cevit, Omer
AU  - Cevit O
FAU - Muderris, Suphi
AU  - Muderris S
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PL  - Turkey
TA  - Kulak Burun Bogaz Ihtis Derg
JT  - Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
JID - 100899230
RN  - 0 (Anti-Allergic Agents)
RN  - 0 (Nasal Sprays)
RN  - 0 (Phthalazines)
RN  - 0 (Pregnadienediols)
RN  - 04201GDN4R (Mometasone Furoate)
RN  - ZQI909440X (azelastine)
SB  - IM
MH  - Administration, Topical
MH  - Adolescent
MH  - Anti-Allergic Agents/*administration & dosage
MH  - Child
MH  - Female
MH  - Humans
MH  - Male
MH  - Mometasone Furoate
MH  - Nasal Cavity/pathology
MH  - Nasal Sprays
MH  - Phthalazines/*administration & dosage
MH  - Pregnadienediols/*administration & dosage
MH  - Rhinitis, Allergic, Perennial/*drug therapy/pathology
MH  - Seawater
MH  - Skin Tests
MH  - Treatment Outcome
EDAT- 2013/07/10 06:00
MHDA- 2015/05/27 06:00
CRDT- 2013/07/10 06:00
PHST- 2013/07/10 06:00 [entrez]
PHST- 2013/07/10 06:00 [pubmed]
PHST- 2015/05/27 06:00 [medline]
AID - kbbihtisas.2013.27132 [pii]
AID - 10.5606/kbbihtisas.2013.27132 [doi]
PST - ppublish
SO  - Kulak Burun Bogaz Ihtis Derg. 2013 Jul-Aug;23(4):217-24. doi: 
      10.5606/kbbihtisas.2013.27132.