PMID- 23835219 OWN - NLM STAT- MEDLINE DCOM- 20140326 LR - 20191210 IS - 1873-4235 (Electronic) IS - 0956-5663 (Linking) VI - 50 DP - 2013 Dec 15 TI - Label-free photoelectrochemical immunosensor based on CdTe/CdS co-sensitized TiO2 nanotube array structure for octachlorostyrene detection. PG - 66-71 LID - S0956-5663(13)00374-6 [pii] LID - 10.1016/j.bios.2013.05.040 [doi] AB - An octachlorostyrene (OCS) photoelectrochemical (PEC) immunosensor was developed by cross-linking anti-OCS antibody onto a CdTe/CdS-sensitized TiO2 nanotube arrays (NTAs). The anti-OCS polyclonal antibody was developed in rabbit as a result of immunization with BSA-OCS hapten conjugate. TiO2 NTAs were immobilized firstly with hydrothermally synthesized CdTe quantum dots (QDs), and then CdS which filled the spaces within the CdTe-TiO2 composite and encapsulated the CdTe QDs, forming an ideal stepwise bandedge structure, which benefited the light harvesting. The PEC immunosensor therefore shows high specificity and high sensitivity with a limit of detection of 2.58 pM, and a linear range from 5 pM to 50 nM. The testing time is 4 min. The analysis of river water reveals that the proposed sensor can be applied in the analysis of OCS in real water samples without complicated pre-treatments. CI - Copyright (c) 2013 Elsevier B.V. All rights reserved. FAU - Cai, Jin AU - Cai J AD - State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China. FAU - Sheng, Pengtao AU - Sheng P FAU - Zhou, Liping AU - Zhou L FAU - Shi, Lei AU - Shi L FAU - Wang, Niya AU - Wang N FAU - Cai, Qingyun AU - Cai Q LA - eng PT - Evaluation Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20130604 PL - England TA - Biosens Bioelectron JT - Biosensors & bioelectronics JID - 9001289 RN - 0 (Cadmium Compounds) RN - 0 (Styrenes) RN - 0 (Sulfides) RN - 0 (Water Pollutants, Chemical) RN - 057EZR4Z7Q (cadmium sulfide) RN - 15FIX9V2JP (titanium dioxide) RN - 304368U4VH (octachlorostyrene) RN - D1JT611TNE (Titanium) RN - NQA0O090ZJ (Tellurium) RN - STG188WO13 (cadmium telluride) SB - IM MH - Animals MH - Cadmium Compounds/*chemistry MH - Electrochemical Techniques/instrumentation MH - Environmental Monitoring/instrumentation MH - Equipment Design MH - Immunoassay/instrumentation MH - Limit of Detection MH - Nanotubes/chemistry MH - Quantum Dots/chemistry MH - Rabbits MH - Rivers/chemistry MH - Styrenes/*analysis MH - Sulfides/*chemistry MH - Tellurium/*chemistry MH - Titanium/*chemistry MH - Water Pollutants, Chemical/*analysis OTO - NOTNLM OT - CdTe/CdS-TiO(2) NTAs OT - Label-free immunosensor OT - Octachlorostyrene OT - Photoelectrochemical EDAT- 2013/07/10 06:00 MHDA- 2014/03/29 06:00 CRDT- 2013/07/10 06:00 PHST- 2013/03/30 00:00 [received] PHST- 2013/05/14 00:00 [revised] PHST- 2013/05/24 00:00 [accepted] PHST- 2013/07/10 06:00 [entrez] PHST- 2013/07/10 06:00 [pubmed] PHST- 2014/03/29 06:00 [medline] AID - S0956-5663(13)00374-6 [pii] AID - 10.1016/j.bios.2013.05.040 [doi] PST - ppublish SO - Biosens Bioelectron. 2013 Dec 15;50:66-71. doi: 10.1016/j.bios.2013.05.040. Epub 2013 Jun 4.