PMID- 23840979
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130710
LR  - 20211021
IS  - 2090-6528 (Print)
IS  - 2090-6536 (Electronic)
VI  - 2013
DP  - 2013
TI  - Desmoplastic small round cell tumor of stomach.
PG  - 907136
LID - 10.1155/2013/907136 [doi]
LID - 907136
AB  - Desmoplastic small round cell tumor (DSRCT) is an extremely uncommon, highly 
      aggressive, and malignant mesenchymal neoplasm of undetermined histogenesis. Less 
      than 200 case reports have been documented in literature so far. Herein, we 
      report a 26-year-old otherwise healthy female patient who presented with a 
      1-month history of epigastric pain. On physical examination, a palpable, slightly 
      mobile, and tender epigastric mass was detected. All laboratory tests were 
      normal. A chest, abdominal, and pelvic contrast-enhanced computed tomography (CT) 
      scans showed a 3.8 x 7.2 x 8.7 cm ill-defined mass, involving gastric fundus and 
      extending into gastric cardia and lower gastroesophageal junction. It was 
      associated with multiple enlarged gastrohepatic lymph nodes; the largest measured 
      1.2 cm. There was no evidence of ascites or retroperitoneal or mesenteric 
      lymphatic metastases. Patient underwent total gastrectomy with D2 
      lymphadenectomy, splenectomy, and antecolic Roux-en-Y esophagojejunal 
      anastomosis. Histopathological examination revealed coexpression of mesenchymal, 
      epithelial, and neural markers. The characteristic chromosomal translocation 
      (t(11; 22)(p13; q12)) was demonstrated on fluorescence in situ hybridization 
      (FISH) technique. Diagnosis of DSRCT of stomach was confirmed. Patient received 
      no postoperative radiotherapy or chemotherapy. A postoperative 3-month followup 
      failed to show any recurrence. In addition, a literature review on DSRCT is 
      included.
FAU - Abu-Zaid, Ahmed
AU  - Abu-Zaid A
AD  - College of Medicine, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi 
      Arabia.
FAU - Azzam, Ayman
AU  - Azzam A
FAU - Alnajjar, Asma
AU  - Alnajjar A
FAU - Al-Hussaini, Hussa
AU  - Al-Hussaini H
FAU - Amin, Tarek
AU  - Amin T
LA  - eng
PT  - Journal Article
DEP - 20130606
PL  - United States
TA  - Case Rep Gastrointest Med
JT  - Case reports in gastrointestinal medicine
JID - 101580185
PMC - PMC3690222
EDAT- 2013/07/11 06:00
MHDA- 2013/07/11 06:01
PMCR- 2013/06/06
CRDT- 2013/07/11 06:00
PHST- 2013/04/27 00:00 [received]
PHST- 2013/05/27 00:00 [accepted]
PHST- 2013/07/11 06:00 [entrez]
PHST- 2013/07/11 06:00 [pubmed]
PHST- 2013/07/11 06:01 [medline]
PHST- 2013/06/06 00:00 [pmc-release]
AID - 10.1155/2013/907136 [doi]
PST - ppublish
SO  - Case Rep Gastrointest Med. 2013;2013:907136. doi: 10.1155/2013/907136. Epub 2013 
      Jun 6.