PMID- 23841087
OWN - NLM
STAT- MEDLINE
DCOM- 20131231
LR  - 20220331
IS  - 2314-6141 (Electronic)
IS  - 2314-6133 (Print)
VI  - 2013
DP  - 2013
TI  - HLA-G/C, miRNAs, and their role in HIV infection and replication.
PG  - 693643
LID - 10.1155/2013/693643 [doi]
LID - 693643
AB  - In recent years, a number of different mechanisms regulating gene expressions, 
      either in normal or in pathological conditions, have been discovered. This review 
      aims to highlight some of the regulatory pathways involved during the HIV-1 
      infection and disease progression, focusing on the novel discovered microRNAs 
      (miRNAs) and their relation with immune system's agents. Human leukocyte antigen 
      (HLA) family of proteins plays a key role because it is a crucial modulator of 
      the immune response; here we will examine recent findings, centering especially 
      on HLA-C and -G, novel players lately discovered to engage in modulation of 
      immune system. We hope to provide novel perspectives useful to find out original 
      therapeutic roads against HIV-1 infection and AIDS progression.
FAU - Celsi, Fulvio
AU  - Celsi F
AD  - Institute for Maternal and Child Health, IRCCS Burlo Garofolo, 34137 Trieste, 
      Italy. celsi@burlo.trieste.it
FAU - Catamo, Eulalia
AU  - Catamo E
FAU - Kleiner, Giulio
AU  - Kleiner G
FAU - Tricarico, Paola Maura
AU  - Tricarico PM
FAU - Vuch, Josef
AU  - Vuch J
FAU - Crovella, Sergio
AU  - Crovella S
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20130613
PL  - United States
TA  - Biomed Res Int
JT  - BioMed research international
JID - 101600173
RN  - 0 (HLA-C Antigens)
RN  - 0 (HLA-G Antigens)
RN  - 0 (MicroRNAs)
SB  - IM
MH  - Acquired Immunodeficiency Syndrome/genetics/virology
MH  - Disease Progression
MH  - HIV Infections/*genetics/pathology/virology
MH  - HIV-1/genetics/pathogenicity
MH  - HLA-C Antigens/*genetics
MH  - HLA-G Antigens/*genetics
MH  - Humans
MH  - Immune System/pathology/virology
MH  - MicroRNAs/*genetics
PMC - PMC3697138
EDAT- 2013/07/11 06:00
MHDA- 2014/01/01 06:00
PMCR- 2013/06/13
CRDT- 2013/07/11 06:00
PHST- 2013/03/21 00:00 [received]
PHST- 2013/05/03 00:00 [revised]
PHST- 2013/05/07 00:00 [accepted]
PHST- 2013/07/11 06:00 [entrez]
PHST- 2013/07/11 06:00 [pubmed]
PHST- 2014/01/01 06:00 [medline]
PHST- 2013/06/13 00:00 [pmc-release]
AID - 10.1155/2013/693643 [doi]
PST - ppublish
SO  - Biomed Res Int. 2013;2013:693643. doi: 10.1155/2013/693643. Epub 2013 Jun 13.