PMID- 23841979 OWN - NLM STAT- MEDLINE DCOM- 20150213 LR - 20140627 IS - 1467-1107 (Electronic) IS - 1047-9511 (Linking) VI - 24 IP - 4 DP - 2014 Aug TI - Pericardiectomy in children <15 years of age. PG - 616-22 LID - 10.1017/S1047951113000814 [doi] AB - Between January, 2002 and December, 2011, 27 patients (19 boys) underwent pericardiectomy. The mean age was 9.3 +/- 4.96 years (range 0.4 to 15 years) and the mean duration of symptoms was 16.9 +/- 22.15 months. In all, 25 patients had dyspnoea; eight were in New York Heart Association (NYHA) class IV; six had bacterial pericarditis; and 18 were on anti-tuberculosis treatment, although only nine had records suggesting tuberculosis. There were nine patients who underwent pre-operative pigtail catheter drainage of pericardial fluid. Surgical procedures were complete pericardiectomy (n = 20), partial pericardiectomy (n = 6), and pleuropericardial window (n = 1).The mean pre-operative right atrial pressure was 20.4 +/- 4.93 mmHg. There were six hospital deaths due to low cardiac output (n = 5) and arrhythmia (n = 1). The mean intensive care unit stay was 2.7 +/- 1.2 days and mean post-operative stay was 9.9 days. The mean right atrial pressure dropped to 8.7 +/- 1.15 mmHg. Adverse outcomes defined as death/prolonged intensive care unit stay, prolonged post-operative stay were not associated with sex, diagnosis of tuberculosis or pyopericardium, or the duration of symptoms or pre-operative right atrial pressure. Younger patients had prolonged intensive care unit stay (p = 0.03) but not increased mortality. Advanced NYHA class predicted death (p = 0.02). The mean follow-up was 23.1 +/- 23.8 months. All except one survivor are in NYHA class I and off all cardiac medications. Despite adequate surgery, pericardiectomy in children is associated with a high mortality, which is related to delayed surgery and poor pre-operative general condition. No specific pre-operative variable other than worse pre-operative NYHA class is a predictor of survival. Therefore, early pericardiectomy should be undertaken in such patients. FAU - Talwar, Sachin AU - Talwar S AD - Cardiothoracic Center and Department of Biostatistics,All India Institute of Medical Sciences,New Delhi,India. FAU - Nair, Vinitha Viswambharan AU - Nair VV AD - Cardiothoracic Center and Department of Biostatistics,All India Institute of Medical Sciences,New Delhi,India. FAU - Choudhary, Shiv Kumar AU - Choudhary SK AD - Cardiothoracic Center and Department of Biostatistics,All India Institute of Medical Sciences,New Delhi,India. FAU - Sreeniwas, Vishnubhatla AU - Sreeniwas V AD - Cardiothoracic Center and Department of Biostatistics,All India Institute of Medical Sciences,New Delhi,India. FAU - Saxena, Anita AU - Saxena A AD - Cardiothoracic Center and Department of Biostatistics,All India Institute of Medical Sciences,New Delhi,India. FAU - Juneja, Rajnish AU - Juneja R AD - Cardiothoracic Center and Department of Biostatistics,All India Institute of Medical Sciences,New Delhi,India. FAU - Kothari, Shyam Sunder AU - Kothari SS AD - Cardiothoracic Center and Department of Biostatistics,All India Institute of Medical Sciences,New Delhi,India. FAU - Airan, Balram AU - Airan B AD - Cardiothoracic Center and Department of Biostatistics,All India Institute of Medical Sciences,New Delhi,India. LA - eng PT - Journal Article DEP - 20130710 PL - England TA - Cardiol Young JT - Cardiology in the young JID - 9200019 SB - IM MH - Adolescent MH - Bacterial Infections/*surgery MH - Child MH - Child, Preschool MH - Cohort Studies MH - Female MH - Humans MH - Infant MH - Length of Stay MH - Male MH - Pericardiectomy/*methods MH - Pericarditis/surgery MH - Pericarditis, Constrictive/*surgery MH - Pericarditis, Tuberculous/*surgery MH - *Postoperative Complications MH - Retrospective Studies MH - Time-to-Treatment EDAT- 2013/07/12 06:00 MHDA- 2015/02/14 06:00 CRDT- 2013/07/12 06:00 PHST- 2013/07/12 06:00 [entrez] PHST- 2013/07/12 06:00 [pubmed] PHST- 2015/02/14 06:00 [medline] AID - S1047951113000814 [pii] AID - 10.1017/S1047951113000814 [doi] PST - ppublish SO - Cardiol Young. 2014 Aug;24(4):616-22. doi: 10.1017/S1047951113000814. Epub 2013 Jul 10.