PMID- 23842655
OWN - NLM
STAT- MEDLINE
DCOM- 20131112
LR  - 20221207
IS  - 2168-6084 (Electronic)
IS  - 2168-6068 (Linking)
VI  - 149
IP  - 9
DP  - 2013 Sep
TI  - Subacute cutaneous lupus erythematosus induced by chemotherapy: gemcitabine as a 
      causative agent.
PG  - 1071-5
LID - 10.1001/jamadermatol.2013.4957 [doi]
AB  - IMPORTANCE: Several chemotherapeutic agents have been reported to induce subacute 
      cutaneous lupus erythematosus (SCLE). To our knowledge, this is the first report 
      to date of SCLE induced by monotherapeutic gemcitabine hydrochloride and includes 
      a comprehensive review of all published cases of chemotherapeutic drug-induced 
      SCLE. OBSERVATIONS: We describe a patient who developed a SCLE-like eruption 
      after being administered gemcitabine and discuss 16 other published cases of 
      chemotherapeutic drug-induced SCLE. CONCLUSIONS AND RELEVANCE: This case and a 
      review of the literature call attention to gemcitabine and other chemotherapeutic 
      agents that have been reported to cause drug-induced SCLE. We also discuss the 
      clinical features of the disease.
FAU - Wiznia, Lauren E
AU  - Wiznia LE
AD  - Department of Dermatology, Yale University School of Medicine, New Haven, 
      Connecticut.
FAU - Subtil, Antonio
AU  - Subtil A
FAU - Choi, Jennifer N
AU  - Choi JN
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - JAMA Dermatol
JT  - JAMA dermatology
JID - 101589530
RN  - 0 (Antimetabolites, Antineoplastic)
RN  - 0 (Antineoplastic Agents)
RN  - 0W860991D6 (Deoxycytidine)
RN  - 0 (Gemcitabine)
SB  - IM
CIN - JAMA Dermatol. 2013 Sep;149(9):1075-6. PMID: 23842706
MH  - Aged
MH  - Antimetabolites, Antineoplastic/*adverse effects
MH  - Antineoplastic Agents/adverse effects
MH  - Deoxycytidine/adverse effects/*analogs & derivatives
MH  - Drug Eruptions/*etiology/pathology
MH  - Female
MH  - Humans
MH  - Lupus Erythematosus, Cutaneous/*chemically induced/pathology
MH  - Gemcitabine
EDAT- 2013/07/12 06:00
MHDA- 2013/11/13 06:00
CRDT- 2013/07/12 06:00
PHST- 2013/07/12 06:00 [entrez]
PHST- 2013/07/12 06:00 [pubmed]
PHST- 2013/11/13 06:00 [medline]
AID - 1710504 [pii]
AID - 10.1001/jamadermatol.2013.4957 [doi]
PST - ppublish
SO  - JAMA Dermatol. 2013 Sep;149(9):1071-5. doi: 10.1001/jamadermatol.2013.4957.