PMID- 23848133
OWN - NLM
STAT- MEDLINE
DCOM- 20140212
LR  - 20220318
IS  - 1755-3768 (Electronic)
IS  - 1755-375X (Linking)
VI  - 91
IP  - 6
DP  - 2013 Sep
TI  - Indocyanine green angiographic and optical coherence tomographic findings support 
      classification of polypoidal choroidal vasculopathy into two types.
PG  - e474-81
LID - 10.1111/aos.12110 [doi]
AB  - PURPOSE: We assessed the characteristic indocyanine green angiographic (ICGA) and 
      spectral domain optical coherence tomographic (SD-OCT) findings of two types of 
      polypoidal choroidal vasculopathy (PCV), distinguishable by different filling 
      patterns on ICGA. METHODS: Thirty-one eyes with PCV were classified into types 1 
      and 2 based on ICGA findings of either the presence or absence of both a feeder 
      and a draining vessel. Characteristic ICGA findings were evaluated for each type 
      of PCV. Spectral domain optical coherence tomographic images of the 31 eyes were 
      also used to compare the two types of PCV. RESULTS: Both a feeder and a draining 
      vessel were observed in 13 eyes (type 1). Eighteen eyes had neither feeder nor 
      draining vessels (type 2). In PCV type 1, a break in the highly reflective line 
      thought to be Bruch's membrane was detected, corresponding to the feeder vessel 
      in-growth site on SD-OCT. This line was straight. In PCV type 2, the highly 
      reflective line exhibited irregular thickness and had highly reflective 
      substances adhering to its lower portion. It curved downward and became 
      increasingly obscure, ultimately disappearing at a point corresponding to the 
      site at which network vessel filling began. The mean subfoveal choroidal 
      thicknesses in eyes with PCV type 1 and PCV type 2 were 199 +/- 65 and 288 +/- 98 mum, 
      respectively. CONCLUSIONS: Our observations support the existence of two distinct 
      types of PCV. The first type represents choroidal neovascularization, whilst the 
      second type involves choroidal vasculature abnormalities.
CI  - (c) 2013 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & 
      Sons Ltd.
FAU - Kawamura, Akiyuki
AU  - Kawamura A
AD  - Department of Ophthalmology, School of Medicine, Nihon University, Tokyo, Japan.
FAU - Yuzawa, Mitsuko
AU  - Yuzawa M
FAU - Mori, Ryusaburo
AU  - Mori R
FAU - Haruyama, Miho
AU  - Haruyama M
FAU - Tanaka, Koji
AU  - Tanaka K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130715
PL  - England
TA  - Acta Ophthalmol
JT  - Acta ophthalmologica
JID - 101468102
RN  - 0 (Coloring Agents)
RN  - IX6J1063HV (Indocyanine Green)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Choroid/*blood supply
MH  - Choroid Diseases/*classification/diagnosis
MH  - Choroidal Neovascularization/classification/diagnosis
MH  - *Coloring Agents
MH  - Female
MH  - *Fluorescein Angiography
MH  - Humans
MH  - *Indocyanine Green
MH  - Male
MH  - Middle Aged
MH  - Ophthalmoscopy
MH  - Peripheral Vascular Diseases/classification/diagnosis
MH  - Polyps/*classification/diagnosis
MH  - *Tomography, Optical Coherence
OTO - NOTNLM
OT  - choroidal neovascularization
OT  - choroidal vasculature abnormality
OT  - indocyanine green angiography
OT  - optical coherence tomography
OT  - polypoidal choroidal vasculopathy
EDAT- 2013/07/16 06:00
MHDA- 2014/02/13 06:00
CRDT- 2013/07/16 06:00
PHST- 2013/07/16 06:00 [entrez]
PHST- 2013/07/16 06:00 [pubmed]
PHST- 2014/02/13 06:00 [medline]
AID - 10.1111/aos.12110 [doi]
PST - ppublish
SO  - Acta Ophthalmol. 2013 Sep;91(6):e474-81. doi: 10.1111/aos.12110. Epub 2013 Jul 
      15.