PMID- 23852104
OWN - NLM
STAT- MEDLINE
DCOM- 20140307
LR  - 20130715
IS  - 1538-1145 (Electronic)
IS  - 1527-4160 (Linking)
VI  - 19
IP  - 4
DP  - 2013 Jul
TI  - Vitamin D insufficiency in psychiatric inpatients.
PG  - 296-300
LID - 10.1097/01.pra.0000432599.24761.c1 [doi]
AB  - OBJECTIVE: The extraskeletal effects of vitamin D have gained increasing 
      attention with the discovery of receptors in a variety of organ systems. Previous 
      work has identified associations between vitamin D insufficiency and a variety of 
      mental illnesses, including affective, cognitive, and psychotic spectrum 
      disorders. We attempted to determine the point prevalence of vitamin D 
      insufficiency among psychiatric inpatients and determine if there was a 
      relationship between vitamin D insufficiency and specific diagnoses and 
      pharmacological treatments. METHODS: This was a retrospective chart review of all 
      adult patients (N=544) admitted to the psychiatric ward of a community hospital 
      in central Illinois between December, 2010 and June, 2011. RESULTS: The mean 
      vitamin D level on admission was 22.3 ng/mL, with a range of 4-79.2 ng/mL. The 
      incidence of vitamin D insufficiency (defined as levels < 30 ng/mL) was 75%. Of 
      those with insufficient levels of vitamin D, only 37% received treatment. Vitamin 
      D insufficiency was not correlated with age, gender, month of admission, length 
      of stay, score on the Global Assessment of Functioning (GAF) scale at admission, 
      diagnosis, or psychotropic medication usage. CONCLUSIONS: Vitamin D insufficiency 
      is highly prevalent in psychiatric inpatients. It is unclear whether this is the 
      result of severe mental illness and resultant social isolation, or if vitamin D 
      has a regulatory role on upstream genes involved in neural networks that 
      influence affect, cognition, and perception.
FAU - Rylander, Melanie
AU  - Rylander M
AD  - University of Colorado School of Medicine, Department of Psychiatry, Denver 
      Health, 777 Bannock St, Denver, CO 80204, USA. mrylander@siumed.edu
FAU - Verhulst, Steven
AU  - Verhulst S
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Psychiatr Pract
JT  - Journal of psychiatric practice
JID - 100901141
RN  - 0 (Vitamins)
RN  - 1406-16-2 (Vitamin D)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Comorbidity
MH  - Female
MH  - Humans
MH  - Illinois/epidemiology
MH  - Incidence
MH  - Inpatients/psychology/*statistics & numerical data
MH  - Male
MH  - Mental Disorders/*epidemiology
MH  - Middle Aged
MH  - Psychiatric Department, Hospital/statistics & numerical data
MH  - Retrospective Studies
MH  - Vitamin D/therapeutic use
MH  - Vitamin D Deficiency/drug therapy/*epidemiology
MH  - Vitamins/therapeutic use
MH  - Young Adult
EDAT- 2013/07/16 06:00
MHDA- 2014/03/08 06:00
CRDT- 2013/07/16 06:00
PHST- 2013/07/16 06:00 [entrez]
PHST- 2013/07/16 06:00 [pubmed]
PHST- 2014/03/08 06:00 [medline]
AID - 00131746-201307000-00006 [pii]
AID - 10.1097/01.pra.0000432599.24761.c1 [doi]
PST - ppublish
SO  - J Psychiatr Pract. 2013 Jul;19(4):296-300. doi: 
      10.1097/01.pra.0000432599.24761.c1.