PMID- 23860892
OWN - NLM
STAT- MEDLINE
DCOM- 20140409
LR  - 20151119
IS  - 1658-3175 (Electronic)
IS  - 0379-5284 (Linking)
VI  - 34
IP  - 7
DP  - 2013 Jul
TI  - Prognostic value of late gadolinium enhancement in dilated cardiomyopathy 
      patients. A meta-analysis.
PG  - 719-26
AB  - OBJECTIVE: To evaluate the prognostic value of late gadolinium enhancement (LGE) 
      in dilated cardiomyopathy (DCM) patients. METHODS: We searched PubMed, MEDLINE, 
      the Cochrane library and EMBASE databases from September to December 2012 in the 
      Renmin Hospital of Wuhan University, Wuhan, China for studies of LGE in DCM 
      patients. We extracted the clinical outcomes (all-cause mortality, cardiovascular 
      mortality, sudden cardiac death [SCD], aborted SCD, heart failure 
      hospitalization) after carefully reviewed. A meta-analysis was performed to 
      calculate pooled odds ratios (OR) with 95% confidence intervals (CIs) for 
      prognostic outcomes in LGE positive versus LGE negative patients with DCM. 
      RESULTS: Five studies for 545 DCM patients were contained in this meta-analysis. 
      The results showed LGE positive patients was significantly associated with higher 
      cardiovascular mortality (pooled OR: 2.67; 95% CI: 1.12-6.35; p=0.03), aborted 
      SCD (pooled OR: 5.26; 95% CI: 1.57-17.55; p=0.007), and heart failure 
      hospitalization (pooled OR: 3.91; 95% CI: 1.99-7.69; p<0.001). CONCLUSION: Late 
      gadolinium enhancement during cardiac MRI is significantly associated with 
      cardiovascular mortality, aborted SCD and heart failure hospitalization in DCM 
      patients. The LGE can be a potential stratification tool to predict the risk of 
      cardiac events among patients with DCM.
FAU - Shi, Hong-Wei
AU  - Shi HW
AD  - Department of Cardiology, Cardiovascular Research Institute, Renmin Hospital of 
      Wuhan University, Hubei, China.
FAU - Pu, Peng
AU  - Pu P
FAU - Deng, Wei
AU  - Deng W
FAU - Zhou, Heng
AU  - Zhou H
FAU - Bian, Zhou-Yan
AU  - Bian ZY
FAU - Shen, Di-Fei
AU  - Shen DF
FAU - Xie, Jing
AU  - Xie J
FAU - Salerno, Michael
AU  - Salerno M
FAU - Tang, Qi-Zhu
AU  - Tang QZ
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PL  - Saudi Arabia
TA  - Saudi Med J
JT  - Saudi medical journal
JID - 7909441
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Cardiomyopathy, Dilated/complications/*diagnosis/*mortality
MH  - *Contrast Media
MH  - Death, Sudden, Cardiac/*etiology
MH  - *Gadolinium
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Predictive Value of Tests
MH  - Time Factors
EDAT- 2013/07/19 06:00
MHDA- 2014/04/10 06:00
CRDT- 2013/07/18 06:00
PHST- 2013/07/18 06:00 [entrez]
PHST- 2013/07/19 06:00 [pubmed]
PHST- 2014/04/10 06:00 [medline]
AID - 0' [pii]
PST - ppublish
SO  - Saudi Med J. 2013 Jul;34(7):719-26.