PMID- 23862974
OWN - NLM
STAT- MEDLINE
DCOM- 20130829
LR  - 20220129
IS  - 1533-4406 (Electronic)
IS  - 0028-4793 (Print)
IS  - 0028-4793 (Linking)
VI  - 369
IP  - 7
DP  - 2013 Aug 15
TI  - Mutations in DSTYK and dominant urinary tract malformations.
PG  - 621-9
LID - 10.1056/NEJMoa1214479 [doi]
AB  - BACKGROUND: Congenital abnormalities of the kidney and the urinary tract are the 
      most common cause of pediatric kidney failure. These disorders are highly 
      heterogeneous, and the etiologic factors are poorly understood. METHODS: We 
      performed genomewide linkage analysis and whole-exome sequencing in a family with 
      an autosomal dominant form of congenital abnormalities of the kidney or urinary 
      tract (seven affected family members). We also performed a sequence analysis in 
      311 unrelated patients, as well as histologic and functional studies. RESULTS: 
      Linkage analysis identified five regions of the genome that were shared among all 
      affected family members. Exome sequencing identified a single, rare, deleterious 
      variant within these linkage intervals, a heterozygous splice-site mutation in 
      the dual serine-threonine and tyrosine protein kinase gene (DSTYK). This variant, 
      which resulted in aberrant splicing of messenger RNA, was present in all affected 
      family members. Additional, independent DSTYK mutations, including nonsense and 
      splice-site mutations, were detected in 7 of 311 unrelated patients. DSTYK is 
      highly expressed in the maturing epithelia of all major organs, localizing to 
      cell membranes. Knockdown in zebrafish resulted in developmental defects in 
      multiple organs, which suggested loss of fibroblast growth factor (FGF) 
      signaling. Consistent with this finding is the observation that DSTYK colocalizes 
      with FGF receptors in the ureteric bud and metanephric mesenchyme. DSTYK 
      knockdown in human embryonic kidney cells inhibited FGF-stimulated 
      phosphorylation of extracellular-signal-regulated kinase (ERK), the principal 
      signal downstream of receptor tyrosine kinases. CONCLUSIONS: We detected 
      independent DSTYK mutations in 2.3% of patients with congenital abnormalities of 
      the kidney or urinary tract, a finding that suggests that DSTYK is a major 
      determinant of human urinary tract development, downstream of FGF signaling. 
      (Funded by the National Institutes of Health and others.).
FAU - Sanna-Cherchi, Simone
AU  - Sanna-Cherchi S
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Sampogna, Rosemary V
AU  - Sampogna RV
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Papeta, Natalia
AU  - Papeta N
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Burgess, Katelyn E
AU  - Burgess KE
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Nees, Shannon N
AU  - Nees SN
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Perry, Brittany J
AU  - Perry BJ
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Choi, Murim
AU  - Choi M
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Bodria, Monica
AU  - Bodria M
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Liu, Yan
AU  - Liu Y
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Weng, Patricia L
AU  - Weng PL
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Lozanovski, Vladimir J
AU  - Lozanovski VJ
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Verbitsky, Miguel
AU  - Verbitsky M
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Lugani, Francesca
AU  - Lugani F
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Sterken, Roel
AU  - Sterken R
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Paragas, Neal
AU  - Paragas N
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Caridi, Gianluca
AU  - Caridi G
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Carrea, Alba
AU  - Carrea A
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Dagnino, Monica
AU  - Dagnino M
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Materna-Kiryluk, Anna
AU  - Materna-Kiryluk A
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Santamaria, Giuseppe
AU  - Santamaria G
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Murtas, Corrado
AU  - Murtas C
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Ristoska-Bojkovska, Nadica
AU  - Ristoska-Bojkovska N
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Izzi, Claudia
AU  - Izzi C
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Kacak, Nilgun
AU  - Kacak N
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Bianco, Beatrice
AU  - Bianco B
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Giberti, Stefania
AU  - Giberti S
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Gigante, Maddalena
AU  - Gigante M
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Piaggio, Giorgio
AU  - Piaggio G
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Gesualdo, Loreto
AU  - Gesualdo L
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Vukic, Durdica Kosuljandic
AU  - Vukic DK
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Vukojevic, Katarina
AU  - Vukojevic K
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Saraga-Babic, Mirna
AU  - Saraga-Babic M
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Saraga, Marijan
AU  - Saraga M
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Gucev, Zoran
AU  - Gucev Z
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Allegri, Landino
AU  - Allegri L
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Latos-Bielenska, Anna
AU  - Latos-Bielenska A
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Casu, Domenica
AU  - Casu D
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - State, Matthew
AU  - State M
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Scolari, Francesco
AU  - Scolari F
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Ravazzolo, Roberto
AU  - Ravazzolo R
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Kiryluk, Krzysztof
AU  - Kiryluk K
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Al-Awqati, Qais
AU  - Al-Awqati Q
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - D'Agati, Vivette D
AU  - D'Agati VD
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Drummond, Iain A
AU  - Drummond IA
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Tasic, Velibor
AU  - Tasic V
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Lifton, Richard P
AU  - Lifton RP
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Ghiggeri, Gian Marco
AU  - Ghiggeri GM
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
FAU - Gharavi, Ali G
AU  - Gharavi AG
AD  - Divisions of Nephrology (S.S.-C., R.V.S., N.P., K.E.B., S.N.N., B.J.P., P.L.W., 
      M.V., F.L., R.S., N.P., N.K., K.K., Q.A.-A., A.G.G.) and Pediatric Nephrology 
      (P.L.W.) and the Department of Pathology (V.D.D.), Columbia University, and the 
      Department of Medicine, St. Luke's-Roosevelt Hospital Center (S.S.-C.), New York; 
      the Department of Genetics, Howard Hughes Medical Institute, and Yale Center for 
      Mendelian Genomics, Yale University, New Haven, CT (M.C., M.S., R.P.L.); the 
      Department of Biomedical Sciences, Seoul National University College of Medicine, 
      Seoul, South Korea (M.C.); the Division of Nephrology, Dialysis, and 
      Transplantation (M.B., F.L., G.C., A.C., M.D., C.M., G.P., G.M.G.) and Laboratory 
      of Molecular Genetics (G.S., R.R.), Istituto Giannina Gaslini, the Division of 
      Nephrology, Department of Internal Medicine (M.B.), and Dipartimento di 
      Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili 
      (R.R.), University of Genoa, and IRCCS San Martino-IST (M.B.), Genoa; Cattedra di 
      Nefrologia, Universita di Brescia, Seconda Divisione di Nefrologia Azienda 
      Ospedaliera Spedali Civili di Brescia Presidio di Montichiari, Brescia (C.I., 
      F.S.); the Department of Clinical Medicine, Nephrology, and Health Sciences, Unit 
      of Nephrology, University of Parma, Parma (B.B., S.G., L.A.); the Department of 
      Medical and Surgical Sciences, University of Foggia, Foggia (M.G.); the 
      Department of Emergency and Organ Transplantation, University of Bari, Bari 
      (L.G.); and the Division of Nephrology and Dialysis, Hospital of Alghero, Alghero 
      (D.C.) - all in Italy; the Nephrology Division, Massachusetts General Hospital 
      (Y.L., I.A.D.), and Department of Genetics, Harvard Medical School (I.A.D.), 
      Charlestown, MA; University Children's Hospital, Medical School of Skopje, 
      Skopje, Macedonia (V.J.L., N.R.-B., Z.G., V.T.); the Department of Medical 
      Genetics, Poznan University of Medical Sciences, Poznan, Poland (A.M.-K., 
      A.L.-B.); and the Department of Pediatrics, University Hospital of Split (D.K.V., 
      M.S.), and the Department of Anatomy, Histology, and Embryology (K.V., M.S.-B.), 
      School of Medicine (M.S.), University of Split, Split, Croatia.
LA  - eng
GR  - K23-DK090207/DK/NIDDK NIH HHS/United States
GR  - UM1 HG006504/HG/NHGRI NIH HHS/United States
GR  - GGP08050/TI_/Telethon/Italy
GR  - HHMI/Howard Hughes Medical Institute/United States
GR  - K23 DK090207/DK/NIDDK NIH HHS/United States
GR  - DK071041/DK/NIDDK NIH HHS/United States
GR  - P01 DK055388/DK/NIDDK NIH HHS/United States
GR  - U54 HG006504/HG/NHGRI NIH HHS/United States
GR  - K08 DK078014/DK/NIDDK NIH HHS/United States
GR  - R01 DK053093/DK/NIDDK NIH HHS/United States
GR  - R01 DK080099/DK/NIDDK NIH HHS/United States
GR  - HG006504/HG/NHGRI NIH HHS/United States
GR  - R01 DK071041/DK/NIDDK NIH HHS/United States
GR  - P30 DK079310/DK/NIDDK NIH HHS/United States
GR  - 1R01DK080099/DK/NIDDK NIH HHS/United States
GR  - R01 DK020999/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20130717
PL  - United States
TA  - N Engl J Med
JT  - The New England journal of medicine
JID - 0255562
RN  - 0 (RNA, Small Interfering)
RN  - EC 2.7.11.1 (Receptor-Interacting Protein Serine-Threonine Kinases)
RN  - EC 2.7.12.1 (DSTYK protein, human)
SB  - IM
CIN - Nat Rev Urol. 2013 Sep;10(9):492. PMID: 23917117
CIN - Am J Kidney Dis. 2014 Feb;63(2):183-5. PMID: 24315771
MH  - Adult
MH  - Animals
MH  - Base Sequence
MH  - Child
MH  - Exome
MH  - Female
MH  - Gene Knockdown Techniques
MH  - Genetic Linkage
MH  - Genome-Wide Association Study
MH  - Heterozygote
MH  - Humans
MH  - Infant
MH  - Kidney/abnormalities
MH  - Male
MH  - Mice
MH  - Molecular Sequence Data
MH  - *Mutation
MH  - Pedigree
MH  - RNA, Small Interfering
MH  - Receptor-Interacting Protein Serine-Threonine Kinases/*genetics/metabolism
MH  - Urinary Tract/*abnormalities/growth & development/metabolism
MH  - Urogenital Abnormalities/*genetics
MH  - Young Adult
PMC - PMC3846391
MID - NIHMS526413
EDAT- 2013/07/19 06:00
MHDA- 2013/08/30 06:00
PMCR- 2014/02/15
CRDT- 2013/07/19 06:00
PHST- 2013/07/19 06:00 [entrez]
PHST- 2013/07/19 06:00 [pubmed]
PHST- 2013/08/30 06:00 [medline]
PHST- 2014/02/15 00:00 [pmc-release]
AID - 10.1056/NEJMoa1214479 [doi]
PST - ppublish
SO  - N Engl J Med. 2013 Aug 15;369(7):621-9. doi: 10.1056/NEJMoa1214479. Epub 2013 Jul 
      17.