PMID- 23869313
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130722
LR  - 20211021
IS  - 2230-8210 (Print)
IS  - 2230-9500 (Electronic)
IS  - 2230-9500 (Linking)
VI  - 17
IP  - 3
DP  - 2013 May
TI  - Hidden diagnosis of multiple endocrine neoplasia-1 unraveled during workup of 
      virilization caused by adrenocortical carcinoma.
PG  - 514-8
LID - 10.4103/2230-8210.111672 [doi]
AB  - Multiple endocrine neoplasia-1 (MEN1) is an autosomal dominant syndrome with 
      classic triad of parathyroid hyperplasia, pancreatic neuroendocrine tumors, and 
      pituitary adenomas. Other recognized manifestations include carcinoid, cutaneous 
      or adrenocortical tumors. It is commonly presented with clinical features related 
      to parathyroid, pancreas or pituitary lesions. Here, we have presented a case 
      that had virilization and biochemical Cushing's syndrome due to adrenocortical 
      carcinoma as presenting feature of MEN1. Cushing's syndrome in MEN1 is an 
      extremely rare and usually late manifestation and most cases are due to 
      corticotropin-producing pituitary adenomas. Although Cushing's syndrome generally 
      develops years after the more typical manifestations of MEN1 appear, it may be 
      the primary manifestation of MEN1 syndrome particularly when related to adrenal 
      adenoma or carcinoma.
FAU - Kharb, Sandeep
AU  - Kharb S
AD  - Department of Endocrinology, Army Hospital (Research and Referral), Delhi Cantt, 
      India.
FAU - Pandit, Aditi
AU  - Pandit A
FAU - Gundgurthi, Abhay
AU  - Gundgurthi A
FAU - Garg, M K
AU  - Garg MK
FAU - Brar, K S
AU  - Brar KS
FAU - Kannan, N
AU  - Kannan N
FAU - Bharwaj, Reena
AU  - Bharwaj R
LA  - eng
PT  - Case Reports
PL  - India
TA  - Indian J Endocrinol Metab
JT  - Indian journal of endocrinology and metabolism
JID - 101555690
PMC - PMC3712387
OTO - NOTNLM
OT  - Adrenocortical carcinoma
OT  - Cushing's syndrome
OT  - multiple endocrine neoplasia-1
OT  - virilizing syndrome
COIS- Conflict of Interest: No
EDAT- 2013/07/23 06:00
MHDA- 2013/07/23 06:01
PMCR- 2013/05/01
CRDT- 2013/07/23 06:00
PHST- 2013/07/23 06:00 [entrez]
PHST- 2013/07/23 06:00 [pubmed]
PHST- 2013/07/23 06:01 [medline]
PHST- 2013/05/01 00:00 [pmc-release]
AID - IJEM-17-514 [pii]
AID - 10.4103/2230-8210.111672 [doi]
PST - ppublish
SO  - Indian J Endocrinol Metab. 2013 May;17(3):514-8. doi: 10.4103/2230-8210.111672.