PMID- 23870893
OWN - NLM
STAT- MEDLINE
DCOM- 20140131
LR  - 20191210
IS  - 1873-7072 (Electronic)
IS  - 0308-8146 (Linking)
VI  - 141
IP  - 3
DP  - 2013 Dec 1
TI  - Simultaneous determination of eighteen steroid hormones in antler velvet by gas 
      chromatography-tandem mass spectrometry.
PG  - 1796-806
LID - S0308-8146(13)00564-5 [pii]
LID - 10.1016/j.foodchem.2013.04.104 [doi]
AB  - A method for the simultaneous determination of eighteen steroid hormones, 
      including 17alpha-ethinylestradiol, 17alpha-estradiol, 19-nortestosterone, estriol, 
      testosterone, androsterone, 17beta-estradiol, estrone, progesterone, 
      17alpha-hydroxyprogesterone, medroxyprogesterone, norethisterone acetate, 
      testosterone 17-propionate, medroxyprogesterone-17-acetate, corticosterone, 
      megestrol-17-acetate, chlromadinone-17-acetate and 17beta-estradiol-benzoate, in 
      antler velvet was developed by solid-phase extraction (SPE) and gas 
      chromatography-tandem mass spectrometry (GC-MS/MS). Prior to the determination by 
      GC-MS/MS, the analytes were derivatized with heptafluorobutyric acid anhydrides 
      (HFBA). The recoveries were in the range of 62.13-104.00% for eighteen compounds 
      at concentration levels (5-500 mug/L) and relative standard deviations (RSDs) were 
      lower than 17.15%. The detection limits were from 0.2 to 22.3 mug/kg for the 
      steroid hormones. The developed method was rapid, sensitive and successfully 
      applied to the determination of steroid hormones in antler velvet samples 
      collected from three countries.
CI  - Copyright (c) 2013 Elsevier Ltd. All rights reserved.
FAU - Lu, Chunmei
AU  - Lu C
AD  - College of Chemistry, Jilin University, Changchun 130012, PR China.
FAU - Wang, Mingtai
AU  - Wang M
FAU - Mu, Jun
AU  - Mu J
FAU - Han, Dachuan
AU  - Han D
FAU - Bai, Yuping
AU  - Bai Y
FAU - Zhang, Hanqi
AU  - Zhang H
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130509
PL  - England
TA  - Food Chem
JT  - Food chemistry
JID - 7702639
RN  - 0 (Steroids)
SB  - IM
MH  - Animals
MH  - Antlers/*chemistry
MH  - Deer
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Molecular Structure
MH  - Steroids/*chemistry
OTO - NOTNLM
OT  - Antler velvet
OT  - Determination
OT  - Gas chromatography-mass spectrometry/mass spectrometry
OT  - Steroid hormones
EDAT- 2013/07/23 06:00
MHDA- 2014/02/01 06:00
CRDT- 2013/07/23 06:00
PHST- 2012/01/12 00:00 [received]
PHST- 2012/07/10 00:00 [revised]
PHST- 2013/04/23 00:00 [accepted]
PHST- 2013/07/23 06:00 [entrez]
PHST- 2013/07/23 06:00 [pubmed]
PHST- 2014/02/01 06:00 [medline]
AID - S0308-8146(13)00564-5 [pii]
AID - 10.1016/j.foodchem.2013.04.104 [doi]
PST - ppublish
SO  - Food Chem. 2013 Dec 1;141(3):1796-806. doi: 10.1016/j.foodchem.2013.04.104. Epub 
      2013 May 9.