PMID- 23872334
OWN - NLM
STAT- MEDLINE
DCOM- 20140515
LR  - 20130930
IS  - 1095-6808 (Electronic)
IS  - 0091-3022 (Linking)
VI  - 34
IP  - 4
DP  - 2013 Oct
TI  - Roles of sex and gonadal steroids in mammalian pheromonal communication.
PG  - 268-84
LID - S0091-3022(13)00038-1 [pii]
LID - 10.1016/j.yfrne.2013.07.004 [doi]
AB  - A brain circuit (the accessory olfactory system) that originates in the 
      vomeronasal organ (VNO) and includes the accessory olfactory bulb (AOB) plus 
      additional forebrain regions mediates many of the effects of pheromones, 
      typically comprised of a variety of non-volatile and volatile compounds, on 
      aspects of social behavior. A second, parallel circuit (the main olfactory 
      system) that originates in the main olfactory epithelium (MOE) and includes the 
      main olfactory bulb (MOB) has also been shown to detect volatile pheromones from 
      conspecifics. Studies are reviewed that point to specific roles of several 
      different steroids and their water-soluble metabolites as putative pheromones. 
      Other studies are reviewed that establish an adult, 'activational' role of 
      circulating sex hormones along with sex differences in the detection and/or 
      processing of non-steroidal pheromones by these two olfactory circuits. 
      Persisting questions about the role of sex steroids in pheromonal processing are 
      posed for future investigation.
CI  - Copyright (c) 2013 Elsevier Inc. All rights reserved.
FAU - Baum, Michael J
AU  - Baum MJ
AD  - Dept. of Biology, Boston University, 5 Cummington St., Boston, MA 02215, USA. 
      Electronic address: baum@bu.edu.
FAU - Bakker, Julie
AU  - Bakker J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20130718
PL  - United States
TA  - Front Neuroendocrinol
JT  - Frontiers in neuroendocrinology
JID - 7513292
RN  - 0 (Gonadal Steroid Hormones)
RN  - 0 (Pheromones)
SB  - IM
MH  - Animals
MH  - Brain/metabolism
MH  - Gonadal Steroid Hormones/*metabolism
MH  - Humans
MH  - Neurons/metabolism
MH  - Olfactory Bulb/metabolism
MH  - Pheromones/*metabolism
MH  - Sexual Behavior/*physiology
MH  - Vomeronasal Organ/metabolism
OTO - NOTNLM
OT  - Estradiol
OT  - Medial amygdala
OT  - Olfactory bulb
OT  - Sexual behavior
OT  - Testosterone
EDAT- 2013/07/23 06:00
MHDA- 2014/05/16 06:00
CRDT- 2013/07/23 06:00
PHST- 2013/05/08 00:00 [received]
PHST- 2013/07/11 00:00 [revised]
PHST- 2013/07/13 00:00 [accepted]
PHST- 2013/07/23 06:00 [entrez]
PHST- 2013/07/23 06:00 [pubmed]
PHST- 2014/05/16 06:00 [medline]
AID - S0091-3022(13)00038-1 [pii]
AID - 10.1016/j.yfrne.2013.07.004 [doi]
PST - ppublish
SO  - Front Neuroendocrinol. 2013 Oct;34(4):268-84. doi: 10.1016/j.yfrne.2013.07.004. 
      Epub 2013 Jul 18.