PMID- 23872889 OWN - NLM STAT- MEDLINE DCOM- 20150123 LR - 20220309 IS - 1614-7499 (Electronic) IS - 0944-1344 (Print) IS - 0944-1344 (Linking) VI - 21 IP - 10 DP - 2014 May TI - Polychlorinated biphenyl levels in the blood of Japanese individuals ranging from infants to over 80 years of age. PG - 6434-9 LID - 10.1007/s11356-013-1965-6 [doi] AB - Individuals' exposure to various persistent organic pollutants (POPs), including polychlorinated biphenyls (PCBs), and its adverse health effects have been a cause of concern. We measured blood PCB concentrations from samples taken from 507 Japanese individuals ranging from infants to those over 80 years of age. The blood PCB levels increased with age for both male (Spearman's r = 0.69, p < 0.001) and female (Spearman's r = 0.70, p < 0.001) participants. Adult men and nulliparous women showed similar increases with age. However, the PCB levels of multiparous women were lower than those of nulliparous women in their thirties (p = 0.005), probably because the PCBs were transferred from the mothers to their children during pregnancy and lactation. Among infants (<2 years of age), some had as high levels of accumulated PCB levels as those in adults >30 years of age. In some cases, the PCB levels were over 0.8 ng/g wet weight, similar to levels observed in adults over 50 years of age. In the future, it will be necessary to do research on the health of the children who are exposed by high concentration level of POPs. FAU - Mori, Chisato AU - Mori C AD - Department of Bioenvironmental Medicine, Graduate School of Medicine, Chiba University, Chiba, 260-8670, Japan, cmori@faculty.chiba-u.jp. FAU - Kakuta, Kazuhiko AU - Kakuta K FAU - Matsuno, Yoshiharu AU - Matsuno Y FAU - Todaka, Emiko AU - Todaka E FAU - Watanabe, Masahiro AU - Watanabe M FAU - Hanazato, Masamichi AU - Hanazato M FAU - Kawashiro, Yukiko AU - Kawashiro Y FAU - Fukata, Hideki AU - Fukata H LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20130720 PL - Germany TA - Environ Sci Pollut Res Int JT - Environmental science and pollution research international JID - 9441769 RN - 0 (Environmental Pollutants) RN - DFC2HB4I0K (Polychlorinated Biphenyls) SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Child MH - Child, Preschool MH - Environmental Exposure/*statistics & numerical data MH - Environmental Pollutants/analysis/*blood MH - Female MH - Humans MH - Infant MH - Infant, Newborn MH - Japan MH - Male MH - Middle Aged MH - Polychlorinated Biphenyls/analysis/*blood MH - Young Adult PMC - PMC4021163 EDAT- 2013/07/23 06:00 MHDA- 2015/01/24 06:00 PMCR- 2013/07/20 CRDT- 2013/07/23 06:00 PHST- 2013/02/03 00:00 [received] PHST- 2013/06/26 00:00 [accepted] PHST- 2013/07/23 06:00 [entrez] PHST- 2013/07/23 06:00 [pubmed] PHST- 2015/01/24 06:00 [medline] PHST- 2013/07/20 00:00 [pmc-release] AID - 1965 [pii] AID - 10.1007/s11356-013-1965-6 [doi] PST - ppublish SO - Environ Sci Pollut Res Int. 2014 May;21(10):6434-9. doi: 10.1007/s11356-013-1965-6. Epub 2013 Jul 20.