PMID- 23881882
OWN - NLM
STAT- MEDLINE
DCOM- 20140318
LR  - 20191210
IS  - 1099-1077 (Electronic)
IS  - 0885-6222 (Linking)
VI  - 28
IP  - 4
DP  - 2013 Jul
TI  - Presence and composition of cathinone derivatives in drug samples taken from a 
      drug test service in Spain (2010-2012).
PG  - 341-4
LID - 10.1002/hup.2296 [doi]
AB  - OBJECTIVE: The aim of this study was to describe the presence and composition of 
      cathinone derivatives (CDs) in drug samples analyzed at a Drug Testing Service. 
      MATERIAL AND METHODS: Data provided by the Drug Testing Service at Energy Control 
      (a Spanish organization working in risk reduction among recreational drug users) 
      were obtained from samples delivered as, or containing CDs, between January 2010 
      and June 2012. Specimens were identified by combining thin layer chromatography 
      and gas chromatography associated with mass spectrometry. RESULTS: Two hundred 
      and thirty-seven (3.8%) of the 6199 samples were delivered as, or contained CDs. 
      22 different CDs were detected, alone or in different combinations. Methylone 
      (24.9%), mephedrone (24.5%), 4-methylethcathinone (9.28%), and 
      methylenedioxypyrovalerone (6.8%) were the most common CDs. These substances were 
      also found in 80 (1.3%) of 6042 samples delivered allegedly containing drugs 
      different from CDs (such as 3,4-methylenedioxy-N-methylamphetamine (MDMA), 
      amphetamines, ketamine...). CONCLUSIONS: Cathinone derivatives were markedly 
      present in the Spanish drug market during the studied period. There is no 
      evidence to conclude that use of CDs will become widespread or relevant for 
      public health, but the phenomenon must be followed, as the potential risks of 
      these new drugs of abuse are substantial.
CI  - Copyright (c) 2013 John Wiley & Sons, Ltd.
FAU - Caudevilla-Galligo, Fernando
AU  - Caudevilla-Galligo F
AD  - Grupo de Intervencion en Drogas de la Sociedad Espanola de Medicina Familiar y 
      Comunitaria-SEMFYC, Madrid, Spain. caudevilla@gmail.com
FAU - Ventura, Mireia
AU  - Ventura M
FAU - Indave Ruiz, Blanca Iciar
AU  - Indave Ruiz BI
FAU - Fornis, Ivan
AU  - Fornis I
LA  - eng
PT  - Journal Article
PL  - England
TA  - Hum Psychopharmacol
JT  - Human psychopharmacology
JID - 8702539
RN  - 0 (Alkaloids)
RN  - 0 (Illicit Drugs)
RN  - 540EI4406J (cathinone)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Alkaloids/*analysis
MH  - Chromatography, Gas/methods/trends
MH  - Chromatography, Thin Layer/methods/trends
MH  - Female
MH  - Humans
MH  - Illicit Drugs/*analysis
MH  - Male
MH  - Middle Aged
MH  - *Risk Reduction Behavior
MH  - Spain
MH  - Substance Abuse Detection/*methods/*trends
MH  - Young Adult
OTO - NOTNLM
OT  - cathinone derivatives
OT  - cathinones
OT  - legal highs
OT  - mephedrone
EDAT- 2013/07/25 06:00
MHDA- 2014/03/19 06:00
CRDT- 2013/07/25 06:00
PHST- 2012/10/03 00:00 [received]
PHST- 2013/01/15 00:00 [revised]
PHST- 2013/01/17 00:00 [accepted]
PHST- 2013/07/25 06:00 [entrez]
PHST- 2013/07/25 06:00 [pubmed]
PHST- 2014/03/19 06:00 [medline]
AID - 10.1002/hup.2296 [doi]
PST - ppublish
SO  - Hum Psychopharmacol. 2013 Jul;28(4):341-4. doi: 10.1002/hup.2296.