PMID- 238834
OWN - NLM
STAT- MEDLINE
DCOM- 19751107
LR  - 20190827
IS  - 0301-5548 (Print)
IS  - 0301-5548 (Linking)
VI  - 34
IP  - 1
DP  - 1975
TI  - Diurnal changes of the 2,3-diphosphoglycerate concentration in human red cells 
      and the influence of posture.
PG  - 11-7
AB  - The 2,3-diphosphoglycerate (2,3-DPG) concentration, oxygen half saturation 
      pressure at pH 7.4 (P50), pH in plasma and red cells, and mean corpuscular 
      hemoglobin concentration (MCHC) of venous blood were determined during 
      unrestricted daily activity (series I) throughout 24 hrs as well as during 
      prolonged bed rest until noon (series II). In series I almost synchronous dirunal 
      behavior of P50 2,3-DPG, and plasma pH as well as red cell pH became 
      significantly apparent with highest values in the afternoon. The [2,3-DPG] 
      yielded most pronounced alterations, which made up to 13.5% of the average day 
      value. During prolonged recumbency the [2,3-DPG] showed a nonsignificant tendency 
      to decline; the P50 remained unchanged throughout that period. The possible 
      reason for the missing [2,3-DPG] increase is a reduced change of red cell pH in 
      series II. An influence of a posture dependent aldosterone secretion either 
      directly on the 2,3-DPG metabloism of indirectly via mediating the red cell pH 
      and thus ruling the formation of this organic PHOSPHORIS COMPOUND IS DISCUSSED.
FAU - Boning, D
AU  - Boning D
FAU - Meiser, U
AU  - Meiser U
FAU - Schweigart, U
AU  - Schweigart U
FAU - Kunze, M
AU  - Kunze M
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Eur J Appl Physiol Occup Physiol
JT  - European journal of applied physiology and occupational physiology
JID - 0410266
RN  - 0 (Diphosphoglyceric Acids)
RN  - 0 (Hemoglobins)
RN  - 4964P6T9RB (Aldosterone)
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Acid-Base Equilibrium
MH  - Adult
MH  - Aldosterone/physiology
MH  - *Circadian Rhythm
MH  - Diphosphoglyceric Acids/*blood
MH  - Erythrocytes/*analysis
MH  - Hemoglobins/analysis
MH  - Humans
MH  - Hydrogen-Ion Concentration
MH  - Male
MH  - Oxygen/blood
MH  - *Posture
MH  - Veins/analysis
OID - NASA: 75208952
EDAT- 1975/01/01 00:00
MHDA- 1975/01/01 00:01
CRDT- 1975/01/01 00:00
PHST- 1975/01/01 00:00 [pubmed]
PHST- 1975/01/01 00:01 [medline]
PHST- 1975/01/01 00:00 [entrez]
AID - 10.1007/BF00999911 [doi]
PST - ppublish
SO  - Eur J Appl Physiol Occup Physiol. 1975;34(1):11-7. doi: 10.1007/BF00999911.