PMID- 23885515
OWN - NLM
STAT- MEDLINE
DCOM- 20130816
LR  - 20221207
IS  - 0091-2174 (Print)
IS  - 0091-2174 (Linking)
VI  - 44
IP  - 4
DP  - 2012
TI  - Depression ratings and antidepressant use among outpatient heart failure 
      patients: implications for the screening and treatment of depression.
PG  - 315-34
AB  - OBJECTIVE: To investigate the characteristics of antidepressant use among heart 
      failure (HF) outpatients. METHODS: Self-reported data on antidepressant use, Beck 
      Depression Inventory (BDI) ratings, and demographics, as well as HF diagnosis 
      severity, was collected from 218 New York Heart Association (NYHA) Classes I-IV 
      HF outpatients (mean age 57.29 years). RESULTS: The overall prevalence of 
      depressive symptoms (BDI > 10) was 43.1% (n = 94); 23.4% had a prior diagnosis of 
      depression. Thirty-three percent of patients were taking antidepressants but, 
      despite this treatment, 64% still showed at least mild-moderate depressive 
      symptoms (BDI > or = 10) compared to 34% of patients not currently receiving 
      antidepressants (p = 0.05). When asked if their mood had improved as a result of 
      antidepressant therapy, 45% reported responses ranging from "halfway back to 
      normal" to no improvement at all; BDI scores were related to self-reports of how 
      well antidepressant therapy affected patient's mood (p < .01). Among patients 
      receiving antidepressants (primarily SSRIs), 26% did not have a formal depression 
      diagnosis prior to receiving antidepressants, and 39.1% reported never having had 
      a dose adjustment in antidepressant medication. Similar numbers of patients were 
      prescribed antidepressants by primary care physicians as mental health providers, 
      while much fewer cardiologists prescribed antidepressants. CONCLUSIONS: Findings 
      provide insight into practice and provider patterns related to antidepressant use 
      in HF. HF patients treated with antidepressants still show high rates of 
      depressed mood, and follow-up and monitoring of effectiveness of antidepressant 
      therapy needs attention. Effective treatment of depression could support improved 
      clinical outcomes and better quality of life for HF patients.
FAU - Jimenez, Jessica A
AU  - Jimenez JA
AD  - SDSU/UCSD Joint Doctoral Program in Public Health and University of California, 
      San Diego. La Jolla, CA, USA.
FAU - Redwine, Laura L
AU  - Redwine LL
FAU - Rutledge, Thomas R
AU  - Rutledge TR
FAU - Dimsdale, Joel E
AU  - Dimsdale JE
FAU - Pung, Meredith A
AU  - Pung MA
FAU - Ziegler, Michael G
AU  - Ziegler MG
FAU - Greenberg, Barry H
AU  - Greenberg BH
FAU - Mills, Paul J
AU  - Mills PJ
LA  - eng
GR  - HL-079891/HL/NHLBI NIH HHS/United States
GR  - R01 HL073355/HL/NHLBI NIH HHS/United States
GR  - HL-57265/HL/NHLBI NIH HHS/United States
GR  - UL1TR00100/TR/NCATS NIH HHS/United States
GR  - HL-073355/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - Int J Psychiatry Med
JT  - International journal of psychiatry in medicine
JID - 0365646
RN  - 0 (Antidepressive Agents)
RN  - 0 (Serotonin Uptake Inhibitors)
SB  - IM
MH  - Antidepressive Agents/*therapeutic use
MH  - Comorbidity
MH  - Depression/diagnosis/*drug therapy/*epidemiology
MH  - Disease Management
MH  - Female
MH  - Heart Failure/*drug therapy/*epidemiology
MH  - Humans
MH  - Male
MH  - Mass Screening/methods
MH  - Middle Aged
MH  - Outpatients/psychology
MH  - Prevalence
MH  - Psychiatric Status Rating Scales
MH  - Selective Serotonin Reuptake Inhibitors/therapeutic use
MH  - Severity of Illness Index
MH  - Treatment Outcome
EDAT- 2012/01/01 00:00
MHDA- 2013/08/21 06:00
CRDT- 2013/07/27 06:00
PHST- 2013/07/27 06:00 [entrez]
PHST- 2012/01/01 00:00 [pubmed]
PHST- 2013/08/21 06:00 [medline]
AID - 10.2190/PM.44.4.c [doi]
PST - ppublish
SO  - Int J Psychiatry Med. 2012;44(4):315-34. doi: 10.2190/PM.44.4.c.