PMID- 23886121
OWN - NLM
STAT- MEDLINE
DCOM- 20140219
LR  - 20190606
IS  - 2476-762X (Electronic)
IS  - 1513-7368 (Linking)
VI  - 14
IP  - 6
DP  - 2013
TI  - Molecular therapy as a future strategy in endometrial cancer.
PG  - 3419-23
AB  - Of all gynecologic cancers, endometrial cancer is the most common cancer in the 
      US and Europe. In addition, it is presently the second most common gynecologic 
      cancer in the world. As a result of increasing menopausal, obese and tamoxifen 
      use women, the incidence of the cancer seems to be on the increase. Surgery is 
      the major treatment, whereas postoperative radiation therapy in high-intermediate 
      risk patients many prevent locoregional recurrence. Adjuvant chemotherapy can 
      improve progression free survival in advanced or recurrent cancers. Molecular 
      targeted therapies are now a focus of attention including anti-vascular 
      endothelial growth factor (VEGF), mammalian target of rapamycin (mTOR) inhibitor 
      and tyrosine kinase inhibitor (TKI). They may provide useful future strategies 
      for control of endometrial malignancies in developing countries and across the 
      world.
FAU - Thanapprapasr, Duangmani
AU  - Thanapprapasr D
AD  - Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, 
      Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. 
      dmngynonc@gmail.com
FAU - Thanapprapasr, Kamolrat
AU  - Thanapprapasr K
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Thailand
TA  - Asian Pac J Cancer Prev
JT  - Asian Pacific journal of cancer prevention : APJCP
JID - 101130625
RN  - 0 (Antineoplastic Agents)
RN  - 0 (Biomarkers, Tumor)
SB  - IM
MH  - Antineoplastic Agents/*therapeutic use
MH  - Biomarkers, Tumor/*antagonists & inhibitors
MH  - Endometrial Neoplasms/*drug therapy/metabolism
MH  - Female
MH  - Humans
MH  - *Molecular Targeted Therapy
EDAT- 2013/07/28 06:00
MHDA- 2014/02/20 06:00
CRDT- 2013/07/27 06:00
PHST- 2013/07/27 06:00 [entrez]
PHST- 2013/07/28 06:00 [pubmed]
PHST- 2014/02/20 06:00 [medline]
AID - 10.7314/apjcp.2013.14.6.3419 [doi]
PST - ppublish
SO  - Asian Pac J Cancer Prev. 2013;14(6):3419-23. doi: 10.7314/apjcp.2013.14.6.3419.