PMID- 23886175
OWN - NLM
STAT- MEDLINE
DCOM- 20140219
LR  - 20190606
IS  - 2476-762X (Electronic)
IS  - 1513-7368 (Linking)
VI  - 14
IP  - 6
DP  - 2013
TI  - Staging with PET-CT in patients with locally advanced non small cell lung cancer 
      is superior to conventional staging methods in terms of survival.
PG  - 3743-6
AB  - BACKGROUND: Of patients with non small cell lung cancer (NSCLC), around one third 
      are locally advanced at the time of diagnosis. Because only a proprotion of stage 
      III patients can be cured by surgery, in order to improve the outcomes, 
      sequential or concurrent chemoradiation, or concurrent chemoradiation with 
      induction or consolidation is offered to the patients with locally advanced 
      NSCLC. Today, PET combined with computerized tomography (PET-CT) is accepted as 
      the most sensitive technique for detecting mediastinal lymph node and 
      extracranial metastases from NSCLC. We aimed to compare PET-CT and conventional 
      staging procedures for decisions regarding curative treatment of locally advanced 
      NSCLC. MATERIALS AND METHODS: A total of 168 consecutive patients were included 
      from Acibadem Kayseri Hospital, Acibadem Adana Hospital and Kayseri Research and 
      Training Hospital in this study. RESULTS: While the median PFS was 13.0 +/- 1.9 
      months in the PET-CT group, it was only 6.0 +/- 0.9 in the others (p<0.001). The 
      median OS values were 20.5 +/- 15.6 and 11.5 +/- 1.5 months, respectively (p<0.001). 
      DISCUSSION: As a result, we found that staging with PET CT has better results in 
      terms of survival staging. This superiority leads to survival advantage in 
      patients with locally advanced NSCLC.
FAU - Mutlu, Hasan
AU  - Mutlu H
AD  - Department of Medical Oncology, Acibadem Kayseri Hospital, Kayseri, Turkey. 
      doktorhasanmutlu@gmail.com
FAU - Buyukcelik, Abdullah
AU  - Buyukcelik A
FAU - Erden, Abdulsamet
AU  - Erden A
FAU - Aslan, Tuncay
AU  - Aslan T
FAU - Akca, Zeki
AU  - Akca Z
FAU - Kaya, Eser
AU  - Kaya E
FAU - Kibar, Mustafa
AU  - Kibar M
FAU - Seyrek, Ertugrul
AU  - Seyrek E
FAU - Yavuz, Sinan
AU  - Yavuz S
FAU - Calikusu, Zuleyha
AU  - Calikusu Z
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Thailand
TA  - Asian Pac J Cancer Prev
JT  - Asian Pacific journal of cancer prevention : APJCP
JID - 101130625
SB  - IM
MH  - Adenocarcinoma/diagnosis/mortality/therapy
MH  - Brain Neoplasms/*mortality/secondary/therapy
MH  - Carcinoma, Non-Small-Cell Lung/diagnosis/*mortality/therapy
MH  - Carcinoma, Squamous Cell/diagnosis/mortality/therapy
MH  - Chemoradiotherapy
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Lung Neoplasms/diagnosis/mortality/therapy
MH  - Lymph Nodes/diagnostic imaging/pathology
MH  - Lymphatic Metastasis
MH  - Male
MH  - Mediastinal Neoplasms/*mortality/secondary/therapy
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - *Positron-Emission Tomography
MH  - Prognosis
MH  - Retrospective Studies
MH  - Survival Rate
MH  - *Tomography, X-Ray Computed
EDAT- 2013/07/28 06:00
MHDA- 2014/02/20 06:00
CRDT- 2013/07/27 06:00
PHST- 2013/07/27 06:00 [entrez]
PHST- 2013/07/28 06:00 [pubmed]
PHST- 2014/02/20 06:00 [medline]
AID - 10.7314/apjcp.2013.14.6.3743 [doi]
PST - ppublish
SO  - Asian Pac J Cancer Prev. 2013;14(6):3743-6. doi: 10.7314/apjcp.2013.14.6.3743.