PMID- 23887044
OWN - NLM
STAT- MEDLINE
DCOM- 20131126
LR  - 20220408
IS  - 1476-6256 (Electronic)
IS  - 0002-9262 (Print)
IS  - 0002-9262 (Linking)
VI  - 178
IP  - 7
DP  - 2013 Oct 1
TI  - Prevalence of diagnosed and undiagnosed type 2 diabetes mellitus among US 
      adolescents: results from the continuous NHANES, 1999-2010.
PG  - 1106-13
LID - 10.1093/aje/kwt088 [doi]
AB  - Although prevalence and incidence of type 2 diabetes mellitus (T2DM) are 
      reportedly increasing among adolescents, national data are lacking, particularly 
      in regard to undiagnosed T2DM. To estimate the prevalence of diagnosed and 
      undiagnosed T2DM among US adolescents, we analyzed a nationally representative 
      cross-section of 11,888 adolescents aged 12-19 years who received a diabetes 
      interview in the Continuous National Health and Nutrition Examination Survey 
      during 1999-2010. Among them, a random subsample of 4,661 adolescents also had 
      fasting blood samples collected. Persons who reported a previous diabetes 
      diagnosis and were either taking no medication or taking an oral hypoglycemic 
      agent (with or without insulin) were classified as having T2DM; persons who 
      reported using insulin alone were classified as having type 1 diabetes. 
      Undiagnosed diabetes was defined as a fasting plasma glucose concentration of 
      >/=126 mg/dL and was assumed to be type 2. In the fasting subsample, 31 diabetes 
      cases (types 1 and 2) were identified, representing a prevalence of 0.84% 
      (weighted 95% confidence interval (CI): 0.51, 1.40) (276,638 cases; 95% CI: 
      134,255, 419,020). Estimates of the prevalences of type 1 and type 2 diabetes 
      were 0.48% (95% CI: 0.23, 1.02) and 0.36% (95% CI: 0.20, 0.67), respectively, 
      indicating that T2DM accounted for 43% of all cases. Further, undiagnosed T2DM 
      prevalence was 0.12% (95% CI: 0.05, 0.31), representing 34% of T2DM cases (40,611 
      cases; 95% CI: 2,850, 78,373). T2DM accounts for approximately half of adolescent 
      diabetes in the United States, and one-third of these cases are undiagnosed.
FAU - Demmer, Ryan T
AU  - Demmer RT
FAU - Zuk, Aleksandra M
AU  - Zuk AM
FAU - Rosenbaum, Michael
AU  - Rosenbaum M
FAU - Desvarieux, Moise
AU  - Desvarieux M
LA  - eng
GR  - DK 63608/DK/NIDDK NIH HHS/United States
GR  - R00 DE-018739/DE/NIDCR NIH HHS/United States
GR  - R01 DE013094/DE/NIDCR NIH HHS/United States
GR  - R00 DE018739/DE/NIDCR NIH HHS/United States
GR  - R01 DE-13094/DE/NIDCR NIH HHS/United States
GR  - P30 DK063608/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20130725
PL  - United States
TA  - Am J Epidemiol
JT  - American journal of epidemiology
JID - 7910653
RN  - 0 (Blood Glucose)
SB  - IM
CIN - Am J Epidemiol. 2014 Feb 1;179(3):396-7. PMID: 24243743
CIN - Am J Epidemiol. 2014 Feb 1;179(3):395-6. PMID: 24243744
CIN - Am J Epidemiol. 2014 Feb 1;179(3):397-9. PMID: 24588008
MH  - Adolescent
MH  - Adult
MH  - Blood Glucose
MH  - Child
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 1/epidemiology
MH  - Diabetes Mellitus, Type 2/*diagnosis/*epidemiology/ethnology
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Nutrition Surveys
MH  - Prevalence
MH  - Sex Distribution
MH  - Socioeconomic Factors
MH  - United States/epidemiology
PMC - PMC3783093
OTO - NOTNLM
OT  - adolescents
OT  - diabetes mellitus
OT  - etiology
OT  - prevalence
OT  - undiagnosed diabetes
EDAT- 2013/07/28 06:00
MHDA- 2013/12/16 06:00
PMCR- 2014/10/01
CRDT- 2013/07/27 06:00
PHST- 2013/07/27 06:00 [entrez]
PHST- 2013/07/28 06:00 [pubmed]
PHST- 2013/12/16 06:00 [medline]
PHST- 2014/10/01 00:00 [pmc-release]
AID - kwt088 [pii]
AID - 10.1093/aje/kwt088 [doi]
PST - ppublish
SO  - Am J Epidemiol. 2013 Oct 1;178(7):1106-13. doi: 10.1093/aje/kwt088. Epub 2013 Jul 
      25.