PMID- 23900298 OWN - NLM STAT- MEDLINE DCOM- 20140422 LR - 20161125 IS - 1364-5528 (Electronic) IS - 0003-2654 (Linking) VI - 138 IP - 19 DP - 2013 Oct 7 TI - A photoelectrochemical immunosensor for tris(2,3-dibromopropyl) isocyanurate detection with a multiple hybrid CdTe/Au-TiO2 nanotube arrays. PG - 5726-33 LID - 10.1039/c3an00956d [doi] AB - In this paper, tris(2,3-dibromopropyl) isocyanurate (TBC) is for the first time as far as we know determined by ultrasensitive photoelectrochemical (PEC) immunoassay using an antibody-modified ternary hybrid CdTe/Au-TiO2 nanotube arrays (NTAs) photoelectrode, developed by the pulse electrodeposition technique. The as-prepared hybrid shows enhanced photon absorption and photocurrent response, which subsequently increased the photoelectrical conversion efficiency in the visible region. TBC-antibody (Ab) was developed in rabbits as a result of immunization with the BSA-TBC conjugate and covalently cross-linked onto the CdTe/Au-TiO2 NTAs. Since the photocurrent is highly dependent on the TiO2 surface properties, the specific interaction between TBC and the antibody results in a sensitive change in the photocurrent, which displayed a linear range of 5.0 x 10(-11) to 5.0 x 10(-5) M and a low detection limit of 5.0 x 10(-11) M for TBC determination. This proposed strategy highlights the application of TiO2 nanotube in visible-light-activated photoelectrochemical biosensing, which could largely reduce the destructive effect of UV light on biomolecules. FAU - Feng, Hui AU - Feng H AD - State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, IN 410082, China. qycai0001@hnu.edu.cn. FAU - Zhou, Liping AU - Zhou L FAU - Li, Jiezhen AU - Li J FAU - Tran T, ThanhThuy AU - Tran T T FAU - Wang, Niya AU - Wang N FAU - Yuan, Lijuan AU - Yuan L FAU - Yan, Zhihong AU - Yan Z FAU - Cai, Qingyun AU - Cai Q LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Analyst JT - The Analyst JID - 0372652 RN - 0 (Cadmium Compounds) RN - 0 (Dental Alloys) RN - 0 (Organophosphates) RN - 0 (Triazines) RN - 0 (gold-titanium alloy) RN - 0 (isocyanuric acid) RN - 126-72-7 (tris(2,3-dibromopropyl)phosphate) RN - NQA0O090ZJ (Tellurium) RN - STG188WO13 (cadmium telluride) SB - IM MH - Animals MH - Biosensing Techniques/*methods MH - Cadmium Compounds/chemistry MH - Dental Alloys/chemistry MH - Electrochemical Techniques/*methods MH - Enzyme-Linked Immunosorbent Assay/methods MH - Immunoassay/methods MH - Nanotubes/*chemistry MH - Organophosphates/chemistry MH - *Photochemical Processes MH - Rabbits MH - Tellurium/chemistry MH - Triazines/chemistry EDAT- 2013/08/01 06:00 MHDA- 2014/04/23 06:00 CRDT- 2013/08/01 06:00 PHST- 2013/08/01 06:00 [entrez] PHST- 2013/08/01 06:00 [pubmed] PHST- 2014/04/23 06:00 [medline] AID - 10.1039/c3an00956d [doi] PST - ppublish SO - Analyst. 2013 Oct 7;138(19):5726-33. doi: 10.1039/c3an00956d.