PMID- 23901254
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130731
LR  - 20211021
IS  - 1177-5467 (Print)
IS  - 1177-5483 (Electronic)
IS  - 1177-5467 (Linking)
VI  - 7
DP  - 2013
TI  - Preoperative study of the inner segment/outer segment junction of photoreceptors 
      by spectral-domain optical coherence tomography as a prognostic factor in 
      patients with epiretinal membranes.
PG  - 1467-70
LID - 10.2147/OPTH.S44837 [doi]
AB  - OBJECTIVE: To demonstrate whether the preoperative integrity of the inner 
      segment/outer segment (IS/OS) junction of photoreceptors studied by 
      spectral-domain optical coherence tomography (SD-OCT) is a prognostic factor in 
      epiretinal membrane surgery. METHODS: We retrospectively studied patients with an 
      idiopathic epiretinal membrane who underwent a 23-gauge vitrectomy to remove this 
      membrane. Best-corrected visual acuity (BCVA) and SD-OCT scans were examined 
      before and 6 months after the surgery. We studied the retinal microstructure, 
      especially the IS/OS junction of the photoreceptors, and evaluated the intergroup 
      differences between patients with an intact layer and those with an irregular or 
      disrupted layer. We applied both the Wilcoxon and Mann-Whitney tests for 
      statistical analysis. RESULTS: In total, 51 eyes from 51 enrolled patients were 
      examined in this study. The postoperative BCVA was significantly better for eyes 
      that had an intact IS/OS junction than for eyes that had an irregular or 
      disrupted IS/OS junction, as preoperatively observed with SD-OCT scans (P < 
      0.001). We also observed an important association between disrupted IS/OS 
      junctions and the presence of cystic macular edema (P < 0.01). CONCLUSION: The 
      presence of an intact IS/OS junction on the preoperative SD-OCT scan was an 
      important predictor of better visual recovery after epiretinal membrane surgery.
FAU - Cobos, E
AU  - Cobos E
AD  - Department of Ophthalmology, Bellvitge University Hospital, Barcelona, Spain.
FAU - Arias, L
AU  - Arias L
FAU - Ruiz-Moreno, Jm
AU  - Ruiz-Moreno J
FAU - Rubio, Mj
AU  - Rubio M
FAU - Garcia-Bru, P
AU  - Garcia-Bru P
FAU - Caminal, Jm
AU  - Caminal J
FAU - Catala-Mora, J
AU  - Catala-Mora J
FAU - Arruga, J
AU  - Arruga J
LA  - eng
PT  - Journal Article
DEP - 20130719
PL  - New Zealand
TA  - Clin Ophthalmol
JT  - Clinical ophthalmology (Auckland, N.Z.)
JID - 101321512
PMC - PMC3720661
OTO - NOTNLM
OT  - epiretinal membrane
OT  - inner segment/outer segment junction
OT  - photoreceptors
OT  - spectral-domain optical coherence tomography
EDAT- 2013/08/01 06:00
MHDA- 2013/08/01 06:01
PMCR- 2013/07/19
CRDT- 2013/08/01 06:00
PHST- 2013/08/01 06:00 [entrez]
PHST- 2013/08/01 06:00 [pubmed]
PHST- 2013/08/01 06:01 [medline]
PHST- 2013/07/19 00:00 [pmc-release]
AID - opth-7-1467 [pii]
AID - 10.2147/OPTH.S44837 [doi]
PST - ppublish
SO  - Clin Ophthalmol. 2013;7:1467-70. doi: 10.2147/OPTH.S44837. Epub 2013 Jul 19.