PMID- 23913018
OWN - NLM
STAT- MEDLINE
DCOM- 20150122
LR  - 20211021
IS  - 1869-1447 (Electronic)
IS  - 1869-1439 (Linking)
VI  - 24
IP  - 2
DP  - 2014 Jun
TI  - Detection of pulsation in unruptured cerebral aneurysms by ECG-gated 3D-CT 
      angiography (4D-CTA) with 320-row area detector CT (ADCT) and follow-up 
      evaluation results: assessment based on heart rate at the time of scanning.
PG  - 145-50
LID - 10.1007/s00062-013-0236-8 [doi]
AB  - PURPOSE: Many epidemiological studies on unruptured cerebral aneurysms have 
      reported that the larger the aneurysm, the higher the risk of rupture. However, 
      many ruptured aneurysms are not large. Electrocardiography (ECG)-gated 
      3D-computed tomography angiography (4D-CTA) was used to detect pulsation in 
      unruptured cerebral aneurysms. The differences in the clinical course of patients 
      in whom pulsation was or was not detected were then evaluated. METHODS: Forty-two 
      patients with 62 unruptured cystiform cerebral aneurysms who underwent 4D-CTA and 
      follow-up 3D-CTA more than 120 days later were studied. The tube voltage, tube 
      current, and rotation speed were 120 kV, 270 mA, and 0.35 s/rot., respectively. 
      ECG-gated reconstruction was performed, with the cardiac cycle divided into 20 
      phases. Patients with heart rates higher than 80 bpm were excluded, so 37 
      patients with 56 aneurysms were analyzed. RESULTS: Pulsation was detected in 20 
      of the 56 unruptured aneurysms. Of these 20 aneurysms, 6 showed a change in shape 
      at the time of follow-up. Of the 36 aneurysms in which pulsation was not 
      detected, 2 showed a change in shape at follow-up. There was no significant 
      difference in the follow-up interval between the two groups. The aneurysms in 
      which pulsation was detected were significantly more likely to show a change in 
      shape (P = 0.04), with a higher odds ratio of 7.286. CONCLUSION: Unruptured 
      aneurysms in which pulsation was detected by 4D-CTA were more likely to show a 
      change in shape at follow-up, suggesting that 4D-CTA may be useful for 
      identifying aneurysms with a higher risk of rupture.
FAU - Hayakawa, M
AU  - Hayakawa M
AD  - Department of Neurosurgery, School of Medicine, Fujita Health University, 
      Toyoake, 470-1192, Aichi, Japan, hayakawa@fujita-hu.ac.jp.
FAU - Tanaka, T
AU  - Tanaka T
FAU - Sadato, A
AU  - Sadato A
FAU - Adachi, K
AU  - Adachi K
FAU - Ito, K
AU  - Ito K
FAU - Hattori, N
AU  - Hattori N
FAU - Omi, T
AU  - Omi T
FAU - Oheda, M
AU  - Oheda M
FAU - Katada, K
AU  - Katada K
FAU - Murayama, K
AU  - Murayama K
FAU - Kato, Y
AU  - Kato Y
FAU - Hirose, Y
AU  - Hirose Y
LA  - eng
PT  - Journal Article
DEP - 20130803
PL  - Germany
TA  - Clin Neuroradiol
JT  - Clinical neuroradiology
JID - 101526693
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Aneurysm, Ruptured/diagnostic imaging
MH  - Cardiac-Gated Imaging Techniques/*methods
MH  - Cerebral Angiography/*methods
MH  - Female
MH  - Follow-Up Studies
MH  - Four-Dimensional Computed Tomography/*methods
MH  - *Heart Rate
MH  - Humans
MH  - Intracranial Aneurysm/*diagnostic imaging/*physiopathology
MH  - Male
MH  - Middle Aged
MH  - Multidetector Computed Tomography/methods
MH  - Prognosis
MH  - *Pulsatile Flow
MH  - Radiographic Image Enhancement/methods
MH  - Radiographic Image Interpretation, Computer-Assisted/methods
MH  - Reproducibility of Results
MH  - Risk Assessment
MH  - Sensitivity and Specificity
EDAT- 2013/08/06 06:00
MHDA- 2015/01/23 06:00
CRDT- 2013/08/06 06:00
PHST- 2012/12/09 00:00 [received]
PHST- 2013/06/24 00:00 [accepted]
PHST- 2013/08/06 06:00 [entrez]
PHST- 2013/08/06 06:00 [pubmed]
PHST- 2015/01/23 06:00 [medline]
AID - 10.1007/s00062-013-0236-8 [doi]
PST - ppublish
SO  - Clin Neuroradiol. 2014 Jun;24(2):145-50. doi: 10.1007/s00062-013-0236-8. Epub 
      2013 Aug 3.