PMID- 2391400 OWN - NLM STAT- MEDLINE DCOM- 19901001 LR - 20191029 IS - 0174-1578 (Print) IS - 0174-1578 (Linking) VI - 160 IP - 2 DP - 1990 TI - Arterial hypotension in ducks adapted to high salt intake. PG - 127-36 AB - A homogeneous group of 8-week-old Pekin ducks was divided into two groups: saltwater (SW) ducks received salt water of gradually increasing salinity (200-600 mOsm.kg-1) from the 8th to 20th week of age; freshwater (FW) ducks were maintained on fresh water but otherwise treated identically. During the course of salt-adaptation SW ducks increased plasma osmolality, Na+ and Cl- levels, and concentrations of the osmoregulatory peptide hormones arginine vasotocin and angiotensin II. The apparent volume of inulin distribution decreased in SW ducks, but blood volume was not reduced. SW ducks also developed arterial hypotension, bradycardia, and reduced cardiac output in the course of salt adaptation. This depressed cardiovascular performance was associated with enhanced vagal restraint of cardiac function and reduced plasma concentrations of norepinephrine. Salt water adaptation did not alter the degrees to which mean arterial pressure and heart rate changed in response to intravenous bolus injections of catecholamines. The same applied to the osmoregulatory peptides which were, however, effective only at supraphysiological concentrations. The Pekin duck, as a bird predisposed for adaptation to high salt loads, presumably adapts to chronic hypertonic saline intake by resetting the central autonomic control of blood pressure to a lower level. FAU - Brummermann, M AU - Brummermann M AD - Max-Planck-Institut fur Physiologische, Bad Nauheim, Federal Republic of Germany. FAU - Simon, E AU - Simon E LA - eng PT - Journal Article PL - Germany TA - J Comp Physiol B JT - Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology JID - 8413200 RN - 0 (Sodium, Dietary) RN - 11128-99-7 (Angiotensin II) RN - W6S6URY8OF (Vasotocin) SB - IM MH - Adaptation, Physiological MH - Angiotensin II/blood/pharmacology MH - Animals MH - Blood Pressure/drug effects/physiology MH - Ducks/*physiology MH - Fresh Water MH - Heart Rate/drug effects/physiology MH - Hypotension/blood/*etiology/physiopathology MH - Seawater MH - Sodium, Dietary/*administration & dosage MH - Vasotocin/blood/pharmacology MH - Water-Electrolyte Balance/physiology EDAT- 1990/01/01 00:00 MHDA- 1990/01/01 00:01 CRDT- 1990/01/01 00:00 PHST- 1990/01/01 00:00 [pubmed] PHST- 1990/01/01 00:01 [medline] PHST- 1990/01/01 00:00 [entrez] AID - 10.1007/BF00300944 [doi] PST - ppublish SO - J Comp Physiol B. 1990;160(2):127-36. doi: 10.1007/BF00300944.