PMID- 23934037
OWN - NLM
STAT- MEDLINE
DCOM- 20140716
LR  - 20220330
IS  - 1875-8312 (Electronic)
IS  - 1569-5794 (Linking)
VI  - 29
IP  - 8
DP  - 2013 Dec
TI  - Quantitative assessment of myocardial strain with displacement encoding with 
      stimulated echoes MRI in patients with coronary artery disease.
PG  - 1779-86
LID - 10.1007/s10554-013-0274-y [doi]
AB  - To determine the diagnostic performance and reproducibility of strain assessment 
      with displacement encoding with stimulated echoes (DENSE) cardiovascular magnetic 
      resonance (CMR) in identifying contractile abnormalities in myocardial segments 
      with late gadolinium enhancement (LGE). DENSE CMR was obtained on short-axis 
      planes of the left ventricle (LV) in 24 patients with suspected coronary artery 
      disease. e1 and e2 strains of LV wall were quantified. Cine MRI was acquired to 
      determine percent systolic wall thickening (%SWT), followed by (LGE) CMR. The 
      diagnostic performance of e1, e2 and %SWT for predicting the presence of LGE was 
      evaluated by receiver operating characteristics (ROC) analysis. Myocardial scar 
      on LGE CMR was observed in 91 (24 %) of 384 segments. The area under ROC curve 
      for predicting the segments with LGE was 0.874 by e1, 0.916 by e2 and 0.828 by 
      %SWT (p = 0.001 between e2 and %SWT). Excellent inter-observer reproducibility 
      was found for strain [Intraclass correlation coefficient (ICC) = 0.962 for e1, 
      0.955 for e2] as compared with %SWT (ICC = 0.790). DENSE CMR can be performed as 
      a part of routine CMR study and allows for quantification of myocardial strain 
      with high inter-observer reproducibility. Myocardial strain, especially e2 is 
      useful in detecting altered abnormal systolic contraction in the segments with 
      myocardial scar.
FAU - Miyagi, Hideki
AU  - Miyagi H
AD  - Department of Radiology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 
      514-8507, Japan.
FAU - Nagata, Motonori
AU  - Nagata M
FAU - Kitagawa, Kakuya
AU  - Kitagawa K
FAU - Kato, Shingo
AU  - Kato S
FAU - Takase, Shinichi
AU  - Takase S
FAU - Sigfridsson, Andreas
AU  - Sigfridsson A
FAU - Ishida, Masaki
AU  - Ishida M
FAU - Dohi, Kaoru
AU  - Dohi K
FAU - Ito, Masaaki
AU  - Ito M
FAU - Sakuma, Hajime
AU  - Sakuma H
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130810
PL  - United States
TA  - Int J Cardiovasc Imaging
JT  - The international journal of cardiovascular imaging
JID - 100969716
RN  - 0 (Contrast Media)
RN  - K2I13DR72L (Gadolinium DTPA)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Area Under Curve
MH  - Biomechanical Phenomena
MH  - Contrast Media
MH  - Coronary Artery Disease/complications/*diagnosis/physiopathology
MH  - Female
MH  - Gadolinium DTPA
MH  - Humans
MH  - *Magnetic Resonance Imaging, Cine
MH  - Male
MH  - Middle Aged
MH  - *Myocardial Contraction
MH  - Myocardial Infarction/*diagnosis/etiology/physiopathology
MH  - Myocardium/pathology
MH  - Observer Variation
MH  - Predictive Value of Tests
MH  - Prospective Studies
MH  - ROC Curve
MH  - Reproducibility of Results
MH  - Ventricular Dysfunction, Left/*diagnosis/etiology/physiopathology
MH  - *Ventricular Function, Left
EDAT- 2013/08/13 06:00
MHDA- 2014/07/17 06:00
CRDT- 2013/08/13 06:00
PHST- 2013/05/23 00:00 [received]
PHST- 2013/08/03 00:00 [accepted]
PHST- 2013/08/13 06:00 [entrez]
PHST- 2013/08/13 06:00 [pubmed]
PHST- 2014/07/17 06:00 [medline]
AID - 10.1007/s10554-013-0274-y [doi]
PST - ppublish
SO  - Int J Cardiovasc Imaging. 2013 Dec;29(8):1779-86. doi: 10.1007/s10554-013-0274-y. 
      Epub 2013 Aug 10.